NFL Week 11 Picks Straight Up, Odds For All 14 Games & Spread Picks

How about that Week 10, eh? It was certainly an interesting one as it seemed like almost every game before the 4 PM ET window was a good one.
Then we saw a few blowouts, followed up with a crazy Lions vs. Texans SNF game. The Dolphins were able to defeat the Rams on Monday Night Football to then cap off the slate.
We’re getting to the point where every week matters more, with playoff position important for some and draft pick position important for others. That can make NFL Week 11 picks tough to gauge, but are we scared? Absolutely not!
NFL Week 11 Picks Straight Up For All 14 Games At DraftKings Sportsbook
Set yourself up for an action-packed Week 11 in the NFL, featuring 14 thrilling matchups to explore! This week’s schedule is filled with excitement, and I’m eager to analyze each game and offer up my NFL Week 11 predictions.
The teams I believe will emerge victorious will be prominently displayed in bold, ensuring you can easily keep track:
- Washington Commanders vs. Philadelphia Eagles (TNF)
- Las Vegas Raiders vs. Miami Dolphins
- Cleveland Browns vs. New Orleans Saints
- Indianapolis Colts vs. New York Jets
- Minnesota Vikings vs. Tennessee Titans
- Green Bay Packers vs. Chicago Bears
- Jacksonville Jaguars vs. Detroit Lions
- Los Angeles Rams vs. New England Patriots
- Baltimore Ravens vs. Pittsburgh Steelers
- Seattle Seahawks vs. San Francisco 49ers
- Atlanta Falcons vs. Denver Broncos
- Kansas City Chiefs vs. Buffalo Bills
- Cincinnati Bengals vs. Los Angeles Chargers (SNF)
- Houston Texans vs. Dallas Cowboys (MNF)
Let’s bring these NFL Week 11 picks to life together, and don’t forget to place your bets with me at DraftKings Sportsbook for an action-packed Sunday!
NFL Week 11 Early Spread Picks & Predictions
Rams vs. Patriots Spread Pick: Sunday, November 17th
I like the Patriots to cover the +5 spread facing the Rams in Week 11 at home, and there are a few reasons to feel optimistic. Playing in Foxborough gives New England a clear edge, especially with rookie quarterback Drake Maye already flashing his potential.
Maye has been effective in keeping New England competitive, and his gamer-mentality could make a difference against a Rams defense that has not been very strong this season, allowing an average of 24.1 points per game. The Rams, after a lackluster performance in Week 10, might find it hard to generate the energy needed for a bounce back win.
Offensively, Los Angeles is ranked 20th in points per game and has struggled with their running game, averaging just 3.8 yards per carry. On the other hand, the Patriots' defense is among the top half of the league for yards allowed per play and points allowed per game, indicating they can handle even more effective offenses.
If New England's defense can limit the Rams' average passing attack, which is only at 7 yards per attempt, Maye and the Patriots have a good chance to cover the spread or even pull off an upset.
Chiefs vs. Bills Spread Pick: Sunday, November 17th
The Bills should have a good chance to cover the -2.5 spread at home against the undefeated Chiefs in Week 11. Betting against Kansas City is tough, but Josh Allen is playing at an MVP level, and the Bills’ offense ranks third in points per game, showing they can score big even against strong defenses.
Allen’s ability to run and pass gives Buffalo an advantage, especially at home where the crowd boosts their energy. Although the Chiefs have been perfect so far, this might be the game where they finally lose.
Kansas City’s defense is strong, allowing only 17.9 points per game, but Buffalo’s offense has shown it can adapt and be explosive, particularly with Allen’s effective passing. Plus, the Chiefs have trouble running the ball, averaging just 3.8 yards per carry, which could hinder their clock control in this game.
Buffalo’s defense, despite some ups and downs, typically performs well at home. With a lively crowd and Allen at the helm, the Bills seem ready to cover the spread and possibly give Kansas City its first defeat.
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NFL Week 11 Odds For All 14 Games Provided By DraftKings Sportsbook, November 2024
My NFL Week 11 picks are now available, and we've compiled the spread odds for each matchup, thanks to DraftKings Sportsbook:
- Commanders +3.5 (-120) vs. Eagles -3.5 (-110)
- Raiders +7 (-105) vs. Dolphins -7 (-115)
- Browns +1 (-112) vs. Saints -1 (-108)
- Colts +4 (-110) vs. Jets -4 (-110)
- Vikings -6 (-108) vs. Titans +6 (-112)
- Packers -5.5 (-110) vs. Bears +5.5 (-110)
- Jaguars +13 (-108) vs. Lions -13 (-112)
- Rams -5 (-108) vs. Patriots +5 (-112)
- Ravens -3 (-118) vs. Steelers +3 (-102)
- Seahawks +6.5 (-110) vs. 49ers -6.5 (-110)
- Falcons +2.5 (-108) vs. Broncos -2.5 (-112)
- Chiefs +2.5 (-112) vs. Bills -2.5 (-108)
- Bengals +1.5 (-108) vs. Chargers -1.5 (-112)
- Texans -7.5 (-105) vs. Cowboys +7.5 (-115)
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Player News
Dak Prescott said George Pickens is “more than a 50-50 catcher.”
Prescott in a Wednesday morning radio interview was effusive in his praise of Pickens, who was traded last week from the Steelers to Dallas in exchange for draft compensation. “You put the ball anywhere in his vicinity, very strong hands,” Prescott said of Pickens. “He’s more than a 50-50 catcher. ... I’m excited for him. I know that we need some help at that position.” Pickens, 24, who has 2,841 receiving yards and 12 touchdowns over three NFL seasons, is widely expected to see more single coverage in Dallas than he did as the unquestioned No. 1 wideout in Pittsburgh. Opposing coverage units won’t be able to shade safeties toward his side of the field with CeeDee Lamb threatening the middle of the field. Pickens shapes up as a volatile WR2/3 in 2025.
The Lions will play the Vikings on Christmas Day.
The Week 17 matchup between longtime NFC North rivals will be available exclusively on Netflix. Coming off a devastating Divisional Round loss to Washington last January, the Lions will be prominently featured by the league in 2025. Jared Goff and the Lions beat Minnesota twice during the 2024 regular season: A 31-29 Week 7 victory in Minnesota and a 31-9 Week 18 drubbing in Detroit. Goff combined to throw for 511 yards, three touchdowns, and no interceptions in those games. Justin Jefferson, meanwhile, was limited to ten catches for 131 yards and a touchdown in the Vikings’ 2024 games against Detroit.
The Eagles will face the Chiefs in Week 2.
The NFL’s trickle of 2025 schedule news includes a Super Bowl rematch in Kansas City, where Patrick Mahomes and company will look for a little revenge after getting bulldozed by the Eagles in Super Bowl LIX, 40-22. Philadelphia’s elite defense held Mahomes to a mere 226 yards on 32 pass attempts, with much of that production coming in fourth quarter garbage time. Jalen Hurts threw of two scores and ran in another as Saquon Barkley was held in check to the tune of 57 scoreless yards on 23 carries. If the Chiefs are to get back at the Eagles in Week 2, they’ll have to do a far better job of protecting Mahomes.
The Athletic’s Mike DeFabo believes RB Kaleb Johnson is a “schematic fit” for the Steelers offense.
Johnson, a third-round draft pick who last month was listed as a co-starter alongside Jaylen Warren on the Pittsburgh depth chart, was a hyper-productive back in Iowa’s zone-based rushing scheme, a system used frequently in Arthur Smith’s run-first offense. Only three college running backs in 2024 logged more zone rushes than Johnson. Johnson’s goals in offseason practices, according to DeFabo, “are to learn the playbook and earn the coaching staff’s trust with the hope of becoming an ‘every-down back’ sooner rather than later.” That might require Johnson to improve his pass blocking. The rookie said he’s worked on that with Warren — one of the best blocking backs in the NFL — in recent days.
The Chiefs will play the Cowboys on Thanksgiving Day.
The Week 13 matchup will bring Patrick Mahomes and the AFC champion Chiefs to Dallas for the day’s late afternoon game. It could be a shootout if key players on both sides are healthy. Dak Prescott heads into the season with George Pickens as a legit WR2 behind CeeDee Lamb, and Mahomes — who has talked this offseason about more explosive plays for the KC offense — will have Xavier Worthy, Travis Kelce, Rashee Rice, and Hollywood Brown at his disposal. Mahomes has faced Dallas once in his NFL career, a Week 11 win in 2021 in which he threw for 260 scoreless yards. The hope for both the league and fantasy managers is that the Cowboys are still in postseason contention by the end of November.
Free agent Gabe Davis will visit the New York Giants.
Cut by the Jaguars after one season last week, Davis visited the 49ers on Monday. New York would be a reunion of sorts, as he played for Giants coach Brian Daboll in Buffalo. The G-Men already have several wideouts capable of stretching the field, but 26-year-old Davis could still be a decent role player in a strong offense. The problem, of course, is that the Giants profile as anything but, but rookie QB Jaxson Dart is comfortable throwing down the field.