Welcome back to another round of MLB Best Bets Today as the 2025 baseball season rolls on. 

Sunday’s baseball slate is loaded up with 15 games on the MLB schedule and every team in action. There are many ways to go for our top MLB picks and predictions, with games going on all day. Let’s focus on two games for our MLB best bets today before dishing out a few baseball player props and other picks to consider. 

Keep in mind, some of these odds or lines could move before first pitch. All bets below are for one unit unless otherwise noted. Without further ado, let’s dive into our MLB Best Bets Today.

 

 

 

MLB Picks, Predictions & Best Bets Today, 6/15

Our MLB Best Bets Today start with an NL West matchup as the Arizona Diamondbacks host the San Diego Padres. Can the D-backs finish off the weekend sweep of their divisional rivals? We’ll also dive into the NL Central clash between the St. Louis Cardinals and Milwaukee Brewers this afternoon. Check out these MLB predictions to make as you enjoy Sunday’s baseball action. 

 

 

 

San Diego Padres vs. Arizona Diamondbacks Predictions: Sunday, June 15th

Our top MLB picks today take us to an NL West clash between the Arizona Diamondbacks and San Diego Padres. The Diamondbacks won the first two games of this weekend series, including a dramatic 9th inning comeback last night. Let’s see if they can go for the sweep on Sunday. 

Diamondbacks starter Merrill Kelly owns a 3.18 ERA and 3.22 FIP entering today’s game. After a couple of shaky starts at the end of May, he has two straight scoreless outings to begin June. The right-hander now boasts a 2.13 ERA and 2.05 FIP over his last six starts with 46 strikeouts over 38 innings in this stretch. He owns a 2.34 ERA over his last 12 starts as well. 

Kelly’s current 17.9% K-BB% is his best since 2020 and his .199 batting average allowed is a career-low mark. He’s been very productive with a 2.34 ERA over his last 12 starts as well. The veteran is on the positive end of his home/road splits today with a 2.59 ERA and .179 BA allowed at home this year. 

Kelly can keep it going against a Padres offense that’s struggling mightily against right-handed pitching lately. Over the past two weeks vs. righties, San Diego has a .276 wOBA (30th in MLB), 77 wRC+ (28th), .292 SLG (30th), and .224 BA (28th). It’s also a subpar offense on the road this season with a .296 wOBA (24th) and 87 wRC+ (25th). 

Besides an 11-run explosion on Tuesday, the Padres enter today averaging just 2.7 runs over their last 10 games. Kelly should limit the lineup, especially with how well he’s pitching. The longtime Diamondback also has a solid 3.36 ERA in his career against San Diego. 

On the other side, Padres starter Nick Pivetta could run into trouble. After starting the season hot, Pivetta has cooled off over the past month. He has a 5.34 ERA over his past six starts with 5 runs allowed in both of his last two outings (vs. SF and LAD). In this third straight divisional matchup, another shaky performance may be coming. 

The Diamondbacks lead the MLB in wOBA, wRC+, OPS, and ISO against right-handed pitching this season. Over the past two weeks vs. righties, they have a .382 wOBA, 144 wRC+, .283 BA, and .241 ISO in the split. Plus, the Arizona offense is elite at home this year (.352 wOBA, 123 wRC+). 

The D-backs’ bats come in hot, averaging 5.9 runs per game over the past nine contests. Meanwhile, Pivetta has been notably worse on the road this year. He has a 4.94 ERA, 4.66 FIP, and .339 wOBA allowed in away starts compared to a 2.40 ERA, 2.18 FIP, and .227 wOBA at home. Take the Diamondbacks for the full game and first five innings. 

 

 

 

St. Louis Cardinals vs. Milwaukee Brewers Predictions: Sunday, June 15th

Let’s now turn our attention to an NL Central showdown between the St. Louis Cardinals and Milwaukee Brewers. A starting pitching matchup of Miles Mikolas vs. Quinn Priester doesn’t exactly scream low-scoring. Yet, that’s the angle we’re going with today for our MLB predictions. 

Priester has been very effectively lately for Milwaukee. He owns a 2.35 ERA over his last 7 outings, with exactly one earned run allowed in 5 of those. The Brewers are using him as both a traditional starter and bulk reliever, but he’s been productive in any role. Priester is expected to get the regular start today, though that could change. 

For what it’s worth, the right-hander boasts a 2.63 ERA across his eight starts this year. Priester doesn’t throw hard or strike out many batters, but he does two things very well. He keeps the ball on the ground, as evidenced by a top-tier 57.7% ground-ball rate (95th percentile). Plus, he’s allowing just a 5.8% barrel rate (81st percentile). 

Priester can continue to pitch well in a favorable home matchup today. The Cardinals have poor numbers vs. righties over the past two weeks with a .283 wOBA (28th), 80 wRC+ (27th), and .228 BA (27th). They also have a below-average road offense this year (.298 wOBA, 88 wRC+). 

On the other side, Mikolas will be looking to bounce back after allowing 6 runs to Toronto last time out. Before that rough outing, though, the St. Louis right-hander had a 2.47 ERA over his previous 8 starts. His season-long 4.48 ERA is very underwhelming, but it’s skewed by only a couple of bad games. 

Mikolas has been better on the road with a 3.08 FIP, compared to a 4.50 FIP at home. He boasts a 1.69 ERA over his last five road starts as well. In 11 career outings in Milwaukee, the veteran has a solid 3.08 ERA. 

Meanwhile, the Brewers have struggled against right-handed pitching over the past week with a .284 wOBA (29th), 79 wRC+ (29th), and .212 BA (26th). They also have one of the league’s worst home offenses, ranking last in wOBA, BA, OPS, and slugging at home this year. 

As risky as it may seem, we’re targeting some unders in this divisional matchup. Take the under for the full game and first five innings as both Priester and Mikolas limit the scoring overall. 

 

 

 

Best MLB Player Prop Bets & Other Picks Today, 6/15