Welcome back to another round of MLB Best Bets Today as the 2025 baseball season rolls on. 

Tuesday’s baseball slate is another loaded one with 15 games on the MLB schedule and every team in action. There are many ways to go for our top MLB picks and predictions, with games going on all day. Let’s focus on two games for our MLB best bets today before dishing out a few baseball player props and other picks to consider. 

Keep in mind, some of these odds or lines could move before first pitch. All bets below are for one unit unless otherwise noted. Without further ado, let’s dive into our MLB Best Bets Today.

MLB Picks, Predictions & Best Bets Today, 6/17

Our MLB Best Bets Today feature Rafael Devers and the San Francisco Giants hosting the Cleveland Guardians. We’ll also dive into MLB picks for the Pittsburgh Pirates vs. Detroit Tigers matchup. Plus, as always, don’t miss some top MLB player prop bets below. Check out these MLB predictions to make as you enjoy Tuesday’s baseball action. 

 

 

 

Pittsburgh Pirates vs. Detroit Tigers Predictions: Tuesday, June 17th

Our MLB Best Bets today start off with an interleague matchup as the Detroit Tigers host the Pittsburgh Pirates. This is a prime bounce-back spot to target the Tigers at home after losing their past two games. Plus, fading the Pirates on the road has been profitable this year. 

Detroit is 18-8 straight-up after a loss this season (69%), winning by 2+ runs in 16 of those 26 games following a loss (61%). Plus, after getting swept by the Dodgers on Opening Weekend, the Tigers have only had one three-game losing streak since. Avoiding losing streaks is why this team is one of the league’s best. 

Tigers starter Casey Mize boasts a 2.95 ERA this season and gets to face a bottom-tier Pirates offense. Mize has admittedly looked shaky in recent starts, but those issues have also come on the road. Meanwhile, he owns a 1.54 ERA with a .269 wOBA allowed at home. Compare that to a 3.82 ERA and .338 wOBA on the road. 

The Detroit right-hander has clearly been more comfortable at home. Mize has allowed only one earned run in each of his four home starts thus far. As for the Pirates, they’re averaging just 2.3 runs per game over the past six games and 2.9 runs over the past 13 games. 

Pittsburgh has one of the worst road offenses in the majors, ranking 29th in road batting average, wOBA, OPS, and wRC+ this year. The Pirates also have poor numbers vs. right-handed pitching, with a .294 wOBA (29th), 84 wRC+ (28th), .656 OPS (29th), and .232 BA (27th). It’s a good matchup for Mize to be effective in. 

On the other side, Pirates starter Bailey Falter has a solid 3.36 ERA and 1.12 WHIP this season. Yet, he also has some worrisome advanced stats. The lefty’s 15.4% K rate (6th percentile) and 16.8% whiff rate (2nd) are very low. Meanwhile, his 43.5% hard-hit rate and 8.4% walk rate are both career-high marks. 

Falter has usually been worse on the road, too. He has a 3.99 ERA and .332 wOBA allowed in his away starts, compared to a 2.96 ERA and .255 wOBA at home. Plus, the last time he faced a tough offense, Falter coughed up 4 runs in just 3.2 innings against the Phillies earlier this month. 

Today presents a tough matchup for Falter. The Tigers are hitting left-handers well this season with a .342 wOBA (3rd in MLB), 123 wRC+ (2nd), and .272 BA (1st) in the split. Over the past two weeks vs. southpaws, Detroit has a .380 wOBA (2nd), 148 wRC+ (2nd), and .293 BA (4th). 

Let’s take the Tigers to cover the runlines for the full game and the first five innings. The Pirates are 10-25 on the road this year while Detroit is 24-11 at home. As mentioned above, it’s bounce-back time for the Tigers after losing their last two. 

 

 

 

Cleveland Guardians vs. San Francisco Giants Predictions: Tuesday, June 17th

The San Francisco Giants made headlines two days ago with the blockbuster trade for Rafael Devers. The All-Star will make his Giants debut tonight as his new team hosts the Cleveland Guardians. Let’s break this game down and make some MLB picks. 

Cleveland starter Slade Cecconi has a 4.26 ERA this season, with a 5.01 FIP and 5.89 xERA that are even worse. The right-hander has had some decent outings, but the underlying stats are concerning. Cecconi is allowing a ton of hard contact with an 18.1% barrel rate (1st MLB percentile) and 48.6% hard-hit rate (7th). He also has a poor .283 xBA (13th). 

Meanwhile, the Giants are crushing right-handed pitching over the past week with a .372 wOBA (4th in MLB), 142 wRC+ (3rd), .853 OPS (5th), and 16.1% walk rate (1st). They’re also a top-10 offense in the split over the past two weeks. 

Plus, San Fran obviously gets an offensive upgrade with Devers now in the heart of the lineup. He’s been one of the league’s best hitters this season, but especially against right-handers. Devers boasts a .904 OPS and .244 ISO vs. righties this year. 

Robbie Ray will be on the mound for the Giants, which bodes well for the home team. The lefty has been lights out lately with a 1.89 ERA and 1.74 FIP over his past nine starts. Ray also has a 1.74 ERA and 1.78 FIP over his last five outings. 

Ray has been great at home as well. He has a 2.00 ERA and 2.92 FIP at home so far with just a .210 batting average allowed. The Guardians, on the other hand, have struggled against left-handed pitching this year (.277 wOBA, 77 wRC+). Over the past two weeks vs. lefties, they’ve been slightly worse with a .269 wOBA and 71 wRC+. 

We should bank on Ray being effective in this matchup, especially pitching at home. Plus, the back end of the San Francisco bullpen is well-rested after not pitching much at all against the Dodgers this past weekend. 

This is also a prime home bounce-back opportunity for San Fran after losing their past two games. The Giants are 22-11 at home this year, including 9-4 in their last 13 home games. They’re also 9-3 at home against American League teams this season. 

Meanwhile, the Guardians are slumping lately. They just got swept on the road at Seattle and are 2-8 over their last 10 games. Cleveland is also just 5-10 in its last 15 road games. 

 

 

 

Best MLB Player Prop Bets & Other Picks Today, 6/17