Bills vs. Lions Predictions, Picks & Odds: NFL Week 15, Sunday 12/15
NFL fans understand that not all games are created equal. And gamblers especially get that. In terms of entertainment value, there is a big difference between a couple of bottom rung teams squaring off with a 40 point over/under. Luckily, that’s not what we have here.
Both Buffalo and Detroit have their eyes set on a bye week in the first round of the NFL playoffs. And this game has one of the highest over/unders of the season at 54.5 points. This should be a fun one folks and, if you don’t already have some skin in the game, we’re here to offer out Bills vs. Lions predictions for NFL Week 15!
Even if you just want to see the Bills vs. Lions odds and have Bills vs. Lions picks of your own, don’t forget to scroll down at the end to see how you can scoop up a $1,500 BetMGM Sportsbook sign-up bonus!
Bills vs. Lions Predictions For NFL Week 15, Sunday 12/15
The NFL is interesting in how it is set up as obviously some teams play eachother far more than others. The Bears and Lions, for instance, have played 189 times. On the other side of the Great Lakes, the Bills and Lions have actually only played 12 times. That’s the nature of these divisions and conference. The last time they played was 2022 when Josh Allen beat Jared Goff 28-25. Prior to that they last played in 2018. Obviously these are much different teams now.
The Bills this year have three losses to the Texans, Ravens, and Rams. Last week’s Rams game saw an insane 86 points scored in a 44-42 battle. The Lions only have one loss coming at the hands of the Tampa Bay Buccaneers. They have won 11 straight since then.
Buffalo Bills: Josh Allen Super Hero
After sending off Stefon Diggs, the Bills have opted for a more balance approach. Rather than have one guy getting 160+ targets each year, they barely have anyone on pace for 100 targets this season. Khalil Shakir would be the closest. They have relied on Josh Allen to distribute the ball and shoulder the load. Last week he became the first quarterback to throw and rush for 3 TDs in the same game.
On defense the Buffalo Bills have been a tough unit, ranking 10th in DVOA per FTN Fantasy. They run a heavy zone scheme that attempts to keep things in front of them. And the return of Matt Milano from a torn bicep should make things even tougher over the middle for tight ends.
Detroit Lions: Firing On All Cylinders
The Detroit Lions no longer need to force the ball to Amon-Ra St. Brown. Not that that is bad idea given how good he is. But they are a much more balanced attack now. They have a great line with two good running backs. They have Jameson Williams to stretch the field. And they have Sam LaPorta as a solid two-way tight end. They spread the ball around and everyone is able to eat. Even Tim Patrick scored two touchdowns last week.
On defense the Lions are just as good, if not better. It’s a shame that Aiden Hutchinson got hurt but a trade for Za’Darius Smith has eased those woes. Per Tim Twentyman of DetroitLions.com, he’s actually third in pressures in the NFL since joining the Lions. On the backend Detroit runs heavy man to man which can be tough on the corners but has allowed the safeties to thrive.
Bills vs. Lions Odds, Spreads, Total & Betting Lines
As promised, the latest Bills vs. Lions odds can be found below courtesy of BetMGM Sportsbook:
- Point Spread: Buffalo Bills +2.5 (-110) vs. Detroit Lions -2.5 (-110)
- Money Line: Buffalo Bills (+120) vs. Detroit Lions (-145)
- Game Total (Over/Under): Over 54.5 (-110) vs. Under 54.5 (-110)
Bills vs. Lions: Detroit Lions -2.5 (-110 at BetMGM Sportsbook)
The Bills are a tremendous team, no doubt. And this should be a great game. But I think what these two teams like to do simply favors the Lions. Not to mention, this game is in Detroit.
The Lions love to run man to man. Which leaves them susceptible to star wide receivers who can beat that coverage. You saw it last week with Puka Nacua having 162 yards. But that’s not really how the Bills are built. They are best dinking and dunking to guys like Khalil Shakir and Sam LaPorta vs. zone. They need Amari Cooper to step up here and he could be in line for one of his better days if he is up to the task. He’s actually yet to play more than 53% of the snaps since joining the team so I wonder if his wrist is bothering him.
The Lions are one of the only teams playing man to man more than half the time. The Bills on the other hand play zone nearly 74% of the time. And that plays right into what guys like Amon-Ra St. Brown, Sam LaPorta, and Jahmyr Gibbs do. Tim Patrick is oddly much better vs. zone than man, as Ahaan Rungta of Parlay Science points out. I like the Lions here to win and cover the 2.5.
Bills vs. Lions Injury Report & Latest News
Finally, let’s take a quick look at the projected starting lineups for both teams heading into tonight’s matchup:
BUF Bills
- DB Rasul Douglas - Out
- T Tylan Grable - Questionable
- S Damar Hamlin - Questionable
- TE Dalton Kincaid - Questionable
- TE Quintin Morris - Questionable
- S Taylor Rapp - Questionable
- DE Dawuane Smoot - Questionable
- LB Baylon Spector - Questionable
- DE Casey Toohill - Questionable
DET Lions
- LB Trevor Nowaske - Out
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