NFL TNF Best Player Prop Picks: Rams vs. 49ers - Thursday, 12/12

We’ve got an all-California Thursday Night Football game to kick off Week 15 with the Los Angeles Rams heading a bit north to take on the NFC West rival San Francisco 49ers. With two teams that have been difficult to trust this season, we’re here to provide our best NFL TNF player prop picks as an alternate approach.
Better yet, we’ll also share a massive $1,500 BetMGM Sportsbook welcome offer to go along with our best Rams vs. 49ers player props to ensure it’s a great TNF matchup!
Best NFL Thursday Night Football Player Prop Picks
Divisional rivalries generally tend to create some closer-than-expected matchups, and with this one already having a spread of just a couple points, NFL TNF player prop picks will certainly be a preferred approach by many. Admittedly, these aren’t the easiest teams to get a read on.
However, we’ve done the digging for you and found two sports that we love. We have LA sitting at 7-6 and San Francisco sitting at 6-7, so they’ve had some up-and-down seasons, but there are still trends to be found. The first of which may surprise and the second of our Rams vs. 49ers player props has some great plus-money odds, so let’s get into our best bets.
Rams vs. 49ers Player Props: George Kittle Under 55.5 Receiving Yards (-110 at BetMGM Sportsbook)
That’s right - we’re starting our NFL TNF player prop picks with an under for a superstar at the TE position. There’s no doubt that 49er George Kittle is as good as it gets, and he just had another standout performance this past Sunday, but that was against a struggling Chicago Bears team.
In fact, we actually like that it has his line higher than we projected it to be given that recent performance. While it was certainly great, when facing better competition like the Buffalo Bills the week prior, Kittle had just one catch for seven yards.
Now, we aren’t expecting that either or saying that the Rams are on par with the Bills, but they did just beat them. In fact, LA held Bills TE Dawson Knox to just five yards on one catch. Along with all that, Kittle has surprisingly struggled against his division rival.
He was injured when these teams met earlier this season, but his woes date back much further. In his past four meetings with the Rams, Kittle has been held to 10, 24, 39 and 30 receiving yards. Even the game prior was a 50-yard performance, and we have to go back to 2020 since he last exceeded that against LA.
It’s not what we would normally expect from him, but for this matchup specifically, we’re starting our NFL TNF player prop picks with George Kittle under 55.5 receiving yards (-110 at BetMGM Sportsbook).
Rams vs. 49ers Player Prop Bets: Kyren Williams 1st Half Anytime TD Scorer (+175 at BetMGM Sportsbook)
We also promised some plus-money odds included with our Rams vs. 49ers player props, and that’s on the LA side of the matchup. Taking RB Kyren Williams to score a touchdown is about the most chalk pick imaginable, which is also why the odds present little to no value.
However, if we isolate him to find the endzone in the first half, we’re getting far better odds, and we aren’t scared about the time constraint. The 49ers defense has been a shell of what it was expected to be for many reasons, including that superstar LB Fred Warner has been banged up all season.
San Francisco’s run defense specifically has been vastly underperforming, and that’s putting it mildly. They’ve given up 19 rushing touchdowns this season, which is tied with the Carolina Panthers for the second-most in the NFL. That’s not the type of company they want to keep, and LA has already been a reason for those struggles.
When these teams met in Week 3, Williams scored two touchdowns, which was in the middle of six straight games with at least one touchdown to begin this year. In his first-ever game against San Francisco last year, he also had a touchdown (scored in the second quarter).
With how much the 49ers run defense has declined, we’re adding to our NFL TNF player prop picks with the unique approach of Kyren Williams to score a first half touchdown (+175 at BetMGM Sportsbook).
Thursday Night Football Player Props At BetMGM Sportsbook
Now that you’ve seen the analysis for our best NFL TNF player prop picks, here are some other Rams vs. 49ers player props at BetMGM Sportsbook to consider:
Passing Yards:
- Matthew Stafford: Over 241.5 (-115) vs. Under 241.5 (-115)
- Brock Purdy: Over 244.5 (-115) vs. Under 244.5 (-115)
Rushing Yards:
- Kyren Williams: Over 71.5 (-115) vs. Under 71.5 (-115)
Receiving Yards:
- Cooper Kupp: Over 63.5 (-110) vs. Under 63.5 (-120)
- Puka Nacua: Over 87.5 (-115) vs. Under 87.5 (-115)
- George Kittle: Over 55.5 (-120) vs. Under 55.5 (-110)
Anytime TD Scorer:
- Kyren Williams: -175
- Isaac Guerendo: -150
- Patrick Taylor: -115
- Puka Nacua: +110
- Cooper Kupp: +140
- George Kittle: +155
- Deebo Samuel: +160
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Player News
Russell Wilson said he chose to play with the Giants because of WR Malik Nabers.
“I came here because of him,” said Wilson about Nabers during a panel at Fanatics Fest over the weekend. “I really wanted to play with someone who is special like him.” As a rookie in 2024, Nabers was targeted 170 times, which was second-most among NFL wide receievers. He also led the Giants with 109 receptions for 1,204 yards and seven touchdowns. Wilson, who will turn 37 years old during the 2025 season, had only one player with 100/1000/7 in a single season (Tyler Lockett in 2020). Wilson signed with the Giants in March following a one-year stint with the Steelers.
The Athletic’s Zak Keefer says we should “look for more emphasis on explosion” from the Chiefs’ passing game this season.
As Keefer notes in the article, Andy Reid “made a point of it all spring” for the Chiefs to “get back to pushing the ball deep down the field.” Per PFF, since 2021, Patrick Mahomes has ranked 21st or lower in ADOT (min. 300 dropbacks), but finished sixth in ADOT in 2018 when he broke out for 5,097-50-12 on his way to winning his first MVP. A lot has changed since Mahomes last aired it out at a high rate. Most notably is the departure of Tyreek Hill in 2022 and Travis Kelce no longer being the spry, explosive playmaker we saw several seasons ago. The Chiefs hope the return of Hollywood Brown and a second year of work for Xavier Worthy will lead to more explosive plays next season, which could spell big things for fantasy managers who decide to take shots on pieces of an offense that ranked 15th in scoring last season.
The Athletic’s James Boyd believes Daniel Jones “has already taken a significant lead” in the Colts’ QB competition.
Jones and Anthony Richardson are supposed to compete for the QB1 job in camp. While Richardson recently said he expects to be ready to go by camp, an offseason shoulder surgery has slowed his progress for the upcoming season, and opened the door for Jones to work almost exclusively with the first team offense. Jones has struggled to look like the player who was taken No. 6 overall by the Giants in 2019, but Richardson’s underwhelming performance in 2024 (1,813-8-12) that was headlined by a 47.7 completion percentage was far worse than any single season of Jones’ six-year career. The Colts will string this competition along for as long as they can — assuming Richardson is healthy enough to play in camp — but Richardson is well behind Jones at this point.
Jets owner Woody Johnson has agreed to purchase a 43 percent stake in Premier League club Crystal Palace.
Johnson will buy his stake from American businessman Jon Textor. According to reports, the deal is worth $254 million pending approval from the Premier League and Women’s Super League. The move will make Johnson partners with two other NFL owners as Commanders principal owner Josh Harris and minority owner David Blitzer own the majority stake in the team along with Steve Parish. The 78-year-old Johnson, who served as United States Ambassador to the United Kingdom from 2017 to 2021, previously attempted to buy fellow Premier League club Chelsea in 2022, but was unsuccessful.
Jaguars signed No. 2 overall pick WR/CB Travis Hunter to a four-year contract.
Per ESPN’s Adam Schefter, Hunter’s $46.65 million contract is fully guaranteed and his "$30.57 million signing bonus is paid entirely upfront. The latter aspect makes him “the first non-quarterback not drafted first overall to receive his entire signing bonus upfront.” Securing such a deal makes sense for a player who could lead his team in overall snaps this season. Hunter, 22, has practiced primarily with the Jacksonville offense this offseason, and Jaguars general manager James Gladstone said Hunter has the “capacity” to play an entire NFL game. “He does not tire,” Gladstone said. “He’s got a spark, he’s got the energy, the capacity from a physical standpoint to be able to be able to do it is certainly there.” Hunter will start the season as the team’s No. 2 wideout behind Brian Thomas, Jr.
ESPN reports that Pennsylvania Governor Josh Shapiro reaffirmed that the state will not provide funding for new sports arenas.
Per the report, Shapiro hopes to bring more sports, including NASCAR, to Pennsylvania, but is “very worried about the overall budget.” The state refrained from financially supporting the Sixers, who “decided to partner with Comcast Spectacor, their current landlord, to build a new arena in South Philadelphia.” Both the Eagles and Steelers could someday be impacted by Shapiro’s decision but the Eagles’ Lincoln Field lease runs through 2032. Per the report, Eagles owner Jeffrey Lurie is “‘torn’ over the idea of replacing the stadium or staying put in the home where they raised their only two Super Bowl championship banners.” It’s unclear whether renovations, strictly speaking, would fall under Shapiro’s “new” stadium policy, but there should be ample time to resolve the issue.