NFL TNF Best Player Prop Picks: Rams vs. 49ers - Thursday, 12/12

We’ve got an all-California Thursday Night Football game to kick off Week 15 with the Los Angeles Rams heading a bit north to take on the NFC West rival San Francisco 49ers. With two teams that have been difficult to trust this season, we’re here to provide our best NFL TNF player prop picks as an alternate approach.
Better yet, we’ll also share a massive $1,500 BetMGM Sportsbook welcome offer to go along with our best Rams vs. 49ers player props to ensure it’s a great TNF matchup!
Best NFL Thursday Night Football Player Prop Picks
Divisional rivalries generally tend to create some closer-than-expected matchups, and with this one already having a spread of just a couple points, NFL TNF player prop picks will certainly be a preferred approach by many. Admittedly, these aren’t the easiest teams to get a read on.
However, we’ve done the digging for you and found two sports that we love. We have LA sitting at 7-6 and San Francisco sitting at 6-7, so they’ve had some up-and-down seasons, but there are still trends to be found. The first of which may surprise and the second of our Rams vs. 49ers player props has some great plus-money odds, so let’s get into our best bets.
Rams vs. 49ers Player Props: George Kittle Under 55.5 Receiving Yards (-110 at BetMGM Sportsbook)
That’s right - we’re starting our NFL TNF player prop picks with an under for a superstar at the TE position. There’s no doubt that 49er George Kittle is as good as it gets, and he just had another standout performance this past Sunday, but that was against a struggling Chicago Bears team.
In fact, we actually like that it has his line higher than we projected it to be given that recent performance. While it was certainly great, when facing better competition like the Buffalo Bills the week prior, Kittle had just one catch for seven yards.
Now, we aren’t expecting that either or saying that the Rams are on par with the Bills, but they did just beat them. In fact, LA held Bills TE Dawson Knox to just five yards on one catch. Along with all that, Kittle has surprisingly struggled against his division rival.
He was injured when these teams met earlier this season, but his woes date back much further. In his past four meetings with the Rams, Kittle has been held to 10, 24, 39 and 30 receiving yards. Even the game prior was a 50-yard performance, and we have to go back to 2020 since he last exceeded that against LA.
It’s not what we would normally expect from him, but for this matchup specifically, we’re starting our NFL TNF player prop picks with George Kittle under 55.5 receiving yards (-110 at BetMGM Sportsbook).
Rams vs. 49ers Player Prop Bets: Kyren Williams 1st Half Anytime TD Scorer (+175 at BetMGM Sportsbook)
We also promised some plus-money odds included with our Rams vs. 49ers player props, and that’s on the LA side of the matchup. Taking RB Kyren Williams to score a touchdown is about the most chalk pick imaginable, which is also why the odds present little to no value.
However, if we isolate him to find the endzone in the first half, we’re getting far better odds, and we aren’t scared about the time constraint. The 49ers defense has been a shell of what it was expected to be for many reasons, including that superstar LB Fred Warner has been banged up all season.
San Francisco’s run defense specifically has been vastly underperforming, and that’s putting it mildly. They’ve given up 19 rushing touchdowns this season, which is tied with the Carolina Panthers for the second-most in the NFL. That’s not the type of company they want to keep, and LA has already been a reason for those struggles.
When these teams met in Week 3, Williams scored two touchdowns, which was in the middle of six straight games with at least one touchdown to begin this year. In his first-ever game against San Francisco last year, he also had a touchdown (scored in the second quarter).
With how much the 49ers run defense has declined, we’re adding to our NFL TNF player prop picks with the unique approach of Kyren Williams to score a first half touchdown (+175 at BetMGM Sportsbook).
Thursday Night Football Player Props At BetMGM Sportsbook
Now that you’ve seen the analysis for our best NFL TNF player prop picks, here are some other Rams vs. 49ers player props at BetMGM Sportsbook to consider:
Passing Yards:
- Matthew Stafford: Over 241.5 (-115) vs. Under 241.5 (-115)
- Brock Purdy: Over 244.5 (-115) vs. Under 244.5 (-115)
Rushing Yards:
- Kyren Williams: Over 71.5 (-115) vs. Under 71.5 (-115)
Receiving Yards:
- Cooper Kupp: Over 63.5 (-110) vs. Under 63.5 (-120)
- Puka Nacua: Over 87.5 (-115) vs. Under 87.5 (-115)
- George Kittle: Over 55.5 (-120) vs. Under 55.5 (-110)
Anytime TD Scorer:
- Kyren Williams: -175
- Isaac Guerendo: -150
- Patrick Taylor: -115
- Puka Nacua: +110
- Cooper Kupp: +140
- George Kittle: +155
- Deebo Samuel: +160
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Player News
Browns coach Kevin Stefanski said “it’s fair to say” Jerome Ford is the team’s top running back right now.
Stefanski was asked about the depth chart with second-round rookie Quinshon Judkins unsigned and away from the team. Fellow rookie Dylan Sampson is also in the mix for touches with Judkins out of the picture, but it sounds like Ford will get the first crack at the starting job. On the other hand, Ford was also out of practice for the first session of training camp while nursing a minor injury. There haven’t been any updates on the issue, so he could be back as soon as Thursday. Still, the injury and Judkins’ absence have created a path for Sampson to carve out a role early in his rookie season.
Bears released S Tarvarius Moore.
A former third-round pick of the 49ers, Moore joined the Bears last offseason but was cut at the end of training camp. He re-signed on the team’s practice squad and was eventually called up, appearing in 11 games in total. He played exclusively on special teams in Chicago but did make 13 career starts on defense in San Francisco. Moore should land on another roster at some point in training camp.
Browns head coach Kevin Stefanski said the team wants to make a decision on their starting quarterback “sooner than later.”
Reading the tea leaves, a quick decision on who starts Week 1 would likely break in favor of one of Cleveland’s veterans. A more drawn process would seemingly give Shedeur Sanders and Dillon Gabriel more time to pick up the playbook and adjust to the NFL’s speed. Assuming neither rookie is in the mix, Joe Flacco and Kenny Pickett will be dueling it out for the starting job early in training camp. Having led the Browns to a playoff berth in 2023, Flacco should be considered the favorite until further notice. None of the Browns’ quarterbacks are on the fantasy radar in single quarterback leagues.
49ers WR Jauan Jennings (contract) practiced in full on Wednesday.
Jennings is reportedly seeking a new contract or a trade before the start of the season, but it was business as usual for the first practice of training camp. The veteran wideout was on the field, practicing in full despite his desire for a new deal. 49ers GM John Lynch has also said that Jennings didn’t formally request a trade. As far as contract stalemates go, this one seems rather amicable. Barring a sudden turn of events, Jennings is on track to open the year as San Francisco’s No. 1 receiver. He should hold onto that role until Brandon Aiyuk is fully recovered from the multi-ligament knee injury he suffered last year.
Cardinals coach Jonathan Gannon said DT Walter Nolen will miss time with a calf injury he suffered while getting ready for training camp.
Arizona’s No. 16 overall pick will head to the sidelines for the start of his first training camp as a pro. Nolen was a high-ceiling defensive tackle at Ole Miss who needed to show more consistency in his game. A lack of practice time isn’t going to do him any favors. Though the Cardinals’ defense should improve in Gannon’s second year on the headset, they aren’t off to a great start.
49ers coach Kyle Shanahan said WR Jacob Cowing suffered a hamstring injury in Wednesday’s practice.
Cowing was a rising star during the 49ers’ spring practices, drawing praise from reporters including The Athletic’s Vic Tafur, who said he could take over some of Deebo Samuel’s vacant gadget touches. Now Cowing will join Brandon Aiyuk and Ricky Pearsall on the sidelines. Aiyuk is recovering from a torn ACL and isn’t expected to be ready for Week 1. Pearsall is dealing with a lingering hamstring issue but isn’t expected to miss much time. Despite airing his desire for a new contract publicly, Jauan Jennings showed up to practice and fully participated on Wednesday, putting any notions of a “hold-in” to bed. If the 49ers can’t field a healthy receiving corps around him, Jennings will project for a gaudy target share out of the gates.