NFL Sleeper Top Picks & Plays for Week 10 Sunday Featuring the 49ers & Lions

It’s already Week 10 of the NFL season, and if you were around for Thursday Night Football, then you already know we have a new partner here at Fantasy Alarm. We’ve joined forces with our friends at Sleeper to introduce their Sleeper Picks feature. With Sleeper Picks, you can choose from a variety of players and stat lines, choose whether that player will have more or less than the given stat, and combine your picks for a chance to increase your payout. If you build enough, you can even multiply your entry up to 100x! So, to help get you started, let’s sort through some of the options available for Sunday’s games and help you have even more fun in Week 10.
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NFL Sleeper Top Picks & Plays for Week 10 Sunday Games
Amon-Ra St. Brown, Detroit Lions
It’s been hard to find a more consistent producer both in fantasy and real life than Amon-Ra St. Brown. In five of the seven games he’s played this season, he’s accumulated more than 100 receiving yards, and in this matchup against a soft Los Angeles Chargers pass defense, he’s set up to do it again. The Chargers are allowing 269 yards to the wide receiver position per game, so even though the stat is one of the higher marks of the week, against this defense, it seems like it could be incredibly low at the end of the day. St. Brown is averaging 11.7 yards per reception, and with what should be a back and forth game as the highest scoring of the week, there will be plenty of opportunity for him to rack up yardage.
Pick: Amon-Ra St. Brown more than 82.5 receiving yards (1.77x)
Christian McCaffrey, San Francisco 49ers
Christian McCaffrey may hold the title of running back, but he’s so much more than that, especially as a receiver and multi-purpose player. On the season, he’s averaging 36.5 receiving yards per game, and this week, he gets a matchup against the Jacksonville Jaguars who are allowing the most receptions per game to the running back position, 7.5 to be exact. With an average of over nine yards per reception, McCaffrey should blow this out of the water. Over the past two games, CMC has been more involved in the passing game, finishing with 51 yards in Week 7 and 64 yards in Week 8. Yes, Deebo Samuel should be back in the lineup, but the winds are going to factor in this game, with gusts expected to be around 30 MPH, limiting Brock Purdy’s downfield passes and sending more targets in McCaffrey’s direction. Even if he only gets his yearly average of four targets this game (which I think is a bare minimum he should see), he should easily clear this mark.
Pick: Christian McCaffrey more than 31.5 receiving yards (1.76x)
Tony Pollard, Dallas Cowboys
I know what you may be thinking. “He hasn’t scored a touchdown since Week 1, so why would I make this play?” Well, I’ll tell you. The Giants have given up the third-most rushing touchdowns this season, allowing 13 in nine games. With Dallas being 17.5 point favorites, Pollard should see a ton of work in the run game, and he couldn’t ask for a better “get right” situation. The Giants rank 28th in rush DVOA, 29th in rush yards per attempt, and 25th in rush yards per game, so everything is aligning for Pollard to finally find the end zone again. At a multiplier of 2.02, I’m squeezing this juice.
Pick: Tony Pollard more than .5 rushing touchdowns (2.02x)
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Player News
The Athletic’s Jourdan Rodrigue reports that Kyren Williams’ contract extension “could be worked out by the end of training camp,” but notes that “the Rams will not pay top-market money for a running back.”
Rodrigue believes that the two sides’ continued contract talk “is a good sign” for an early extension. “Williams is a team leader and one of the more productive at his position,” but “he doesn’t hit ‘home run’ explosives,” which hurts his negotiating power, particularly at a position considered low-value by some. Still, Williams’ overall productivity works in his favor. Rodrigue notes, “training camp is the usual timeline for such deals under this era of Rams leadership,” giving fantasy managers an expected timeline to follow.
Patriots LB Jahlani Tavai stayed in New England following June’s mandatory minicamp to rehab his calf injury “in hopes of being ready for the start of training camp.”
The Patriots’ first training camp practice is scheduled for July 23rd. This report fails to provide clarity on Tavai’s expected participation status, though ESPN’s Mike Reiss does list LBs Christian Elliss and Jack Gibbens as Tavai’s “projected top competition” for the No. 2 inside linebacker job. Free agent signee, LB Robert Spillane, is locked into the No. 1 spot.
The NFLPA released a statement in support of Executive Director Lloyd Howell.
Howell came under scrutiny after it was revealed last week that he worked part-time as a paid consultant for The Carlyle Group, which is a private equity firm. On Sunday, the NFLPA released a statement that it rejects “attempts to mischaracterize the committee’s views or divide membership” regarding this news, while adding any reports of the NFLPA calling for Howell to step down are false. It would appear Howell, who was appointed to his position in 2023, will remain in his role for the upcoming season.
Browns RB Quinshon Judkins was charged with misdemeanor domestic battery in Fort Lauderdale, Florida.
Details around Judkins’ arrest continue to emerge. On Sunday, Sergeant David Soika of the shared that upon arriving at the scene where the reported crime took place, officers determined after speaking to the victim that a battery occurred, which led to the arrest of Judkins soon after. The rookie second-rounder remained in police custody overnight and is scheduled to have an initial hearing on Sunday. As ProFootballTalk’s Mike Florio points out, Judkins is sure to face scrutiny from the NFL under the league’s Personal Conduct Policy, while Florio also notes that “the baseline punishment for a battery is six games,” which can vary based on other factors. Judkins has not yet signed his rookie deal, and will likely take less guaranteed money than he hoped for following his arrest, which could cause a trickle-down effect for the 29 other rookie second-rounders who have yet to sign their deal. Judkins was expected to compete for the Browns’ RB1 spot in training camp, and while he will still get a chance to do so, fantasy managers should remain open to the possibility of a suspension being handed down at some point this season. In any case, Jerome Ford rookie Dylan Sampson would both see slight boosts to their fantasy stocks if Judkins were to miss any time.
Browns RB Quinshon Judkins has been arrested and held on domestic violence charges in Fort Lauderdale, Fla.
Judkins was booked on Saturday and remains in custody as of this evening. ESPN’s Daniel Oyefusi reports Judkins’ initial court appearance will come Sunday morning. The Browns have said they are “aware and gathering more details.” Judkins’ arrest comes on the eve of training camp, and gets his professional career off to the worst possible start. A lengthy stay on the commissioner’s exempt list would be all but guaranteed if the charges stick. A suspension would then follow if he were convicted or admitted guilt. The situation should be updated on Sunday.
NFL Network’s Ian Rapoport reports Chargers second-round WR Tre Harris did not report with fellow rookies.
That effectively makes Harris a holdout, something that has become common practice for second-round players amidst ongoing negotiations regarding guaranteed money. 30 of the 32 second-round selections from the 2025 NFL Draft have yet to sign their rookie contracts, with Harris now the first official holdout after the Chargers’ rookie report date came and went. This appears to be nothing more than “just business,” but fantasy managers will want to track the ongoing behind-the-scenes saga unfolding this year.