MLB Best Bets Today, 5/28: Picks, Predictions & Player Props - Wednesday
Welcome to tonight’s MLB best bets for this slate of MLB action here at Fantasy Alarm on this Wednesday, May 28th, 2025! As things stand halfway through the work week, I am 5-4 straight up heading into today’s early slate of games that start right around your lunch breaks! All 30 teams are in action, so no shortage of angles and wagers from me. Check them out below and let’s stay in the green together!
In this MLB Best Bets Today article, you will find a wide array of choices from some Money Lines to game totals and, on occasion, some player props! Check out the rationale and if you agree with me, make sure to tail and good luck!
Now, let's dive into my expert MLB Best Bets today!
- Season Record: 103-75-4
- Bankroll: +13.9 units
Follow me on twitter @jwaggs10
MLB Picks, Predictions & Best Bets Today, 5/28
Twins vs. Rays Predictions
In the early afternoon window today, there’s going to be a hell of a pitchers' duel underway, and it’s the Twins and Rays going at it for the final time in their series. Drew Rasmussen will start for the home team, and he’s been excellent in the month of May, allowing just 6 runs over 21.1 innings pitched and only 17 total hits! In addition to that, he is riding a shutout streak over the past 12 innings, so the Twins' offense will be facing an uphill climb.
On the mound for Minnesota will be Pablo Lopez, and he’s been awesome all season long with an ERA of 2.31 and 54 strikeouts over 50.2 innings pitched. He also allowed just 1 run over his last 11.2 innings pitched. His play will be needed as the Twins' offense has gone cold in the last 5 games, scoring only 15 runs, and they should struggle again today. Give me the under on the runs for the 1st 5 innings while these two pitchers are out there on the mound.
In addition to betting on a lack of runs, I also like Lopez to rack up some strikeouts against a Rays team that is 8th in team K-rate at 22.6% against right-handed pitchers. His line today is 5.5 strikeouts, and seeing as he’s done this in 6 of his last 7 starts and averages over a K per inning, I think he gets the job done again today for us wagerers.
Pick: Twins & Rays 1st 5 Innings Under 4.5 Runs (-145 on DraftKings)
Pick: Pablo Lopez (MIN) Over 5.5 Strikeouts (-130 on DraftKings)
Marlins vs. Padres Predictions
It gives me no joy to say this here today, but Sandy Alcantara is a bad pitcher right now. The road back from his injury has been a rocky one, and he’s still not fully there, so we have to attack that. The former ace has an ERA of 7.71 in the month of May, allowing 19 runs and 23 hits over just 4 starts, and it's hard to see that getting better today against this behemoth of a San Diego lineup.
Over the last 3 games, the Padres have snapped out of their slump and have posted 17 total runs in 3 straight wins, and today they’ll be going for the series sweep. It could be a tough ask, though, to bet on the Padres at -165, so instead I am going to invest in the total as Kyle Hart will start for the Padres, and he’s not very good. In his 5 starts this season, Hart has an ERA of 6.00 and has just 16 strikeouts, and has allowed 23 hits over 21 innings pitched. The Marlins' offense isn’t dynamic, but they should have enough to disrupt the Padres starter. The total sits at 8.5 runs, and that’s an over I will just have to take.
In addition to the total, let’s grab a Padre bat to help us get there! Alcantara has allowed a batting average of .348 in road starts this season, and he’s bad against both lefties and righties, so let’s just pick the hottest hitter. That hitter would be Manny Machado, who is hitting .357 with a 1.169 OPS over the past 7 games, which includes 3 home runs, 10 hits, and 6 runs scored. His hits/runs/RBIs prop is juiced a bit at -150, but to go over 1.5 the way he is hitting just seems like a slam dunk bet to make.
Pick: Marlins & Padres Over 8.5 Runs (-105 on DraftKings)
Pick: Manny Machado (SD) Over 1.5 Hits/Runs/RBIs (-150 on DraftKings)
Best MLB Prop Bets & Other Picks Today, 5/28
Pick: Brent Rooker (ATH) Over 1.5 Hits/Runs/RBIs (-115 on DraftKings)
Pick: Cal Raleigh (SEA) Over 1.5 Hits/Runs/RBIs (-145 on DraftKings)
Pick: Phillies Money Line (-150 on DraftKings)
Pick: Giants & Tigers Over 7.5 Runs (-115 on DraftKings)
Player News
Manny Machado went 2-for-4 with an RBI in a loss to the Marlins on Wednesday.
Jesús Sánchez hit a two-run homer to help the Marlins to a win Wednesday over the Padres.
Calvin Faucher worked the final 1 2/3 innings to pick up a save Wednesday versus the Padres.
Dylan Cease allowed three runs over five innings while picking up a loss to the Marlins on Wednesday.
Sandy Alcantara was credited with a win after allowing just an unearned run over seven innings to help the Marlins to a 3-2 victory over the Padres on Wednesday.
Carlos Correa is not in the lineup for Wednesday’s game against the Dodgers.
It appears to just be a day of rest for Correa. The 30-year-old shortstop gets a break after scoring four runs in Tuesday’s win over Los Angeles, and Brooks Lee will hit ninth and play shortstop in Correa’s absence.