Saints vs. Chargers Predictions, Picks & Odds: NFL Week 8, Sunday 10/27

The NFL Week 8 slate features several divisional rivalries, but one of the matchups that we don’t see nearly as often is one that will be at SoFi Stadium with the Los Angeles Chargers hosting the New Orleans Saints. Both teams have work to do when it comes to maintaining relevance in the playoff race, and we’ve got our best Saints vs. Chargers predictions for you.
Alongside the best bet from our Saints vs. Chargers picks will be a monster $1,500 BetMGM Sportsbook new user promo!
Saints vs. Chargers Predictions for NFL Week 8, Sunday 10/27
The last time we saw a Saints vs. Chargers matchup was back in 2020, so it’s safe to say that both teams look very different. Truthfully, that could be said if these teams had played just last season, or better yet, as recently as the first few weeks of this year!
After just the first two weeks of the season, we had folks discussing the Saints as Super Bowl contenders thanks to outscoring opponents by a whopping 91-29. Well, that was very short-lived, as they’ve since lost five straight.
The last we saw the Chargers, they were the final team of Week 7 to suffer a loss as the second game of the Monday doubleheader, which also came in the final seconds. While these teams are struggling to find their footing, we’ve still got a top pick from our Saints vs. Chargers predictions for you.
New Orleans Saints: Relying On Rattler
An argument can be made that New Orleans’ struggles have been due to the fact that an injury to QB Derek Carr has forced them to thrust rookie QB Spencer Rattler into the spotlight. It’s certainly a legitimate take, but their downturn began even prior to that.
Regardless, it looks as though they’ll be relying on Rattler yet again in Week 8. We saw Carr return to the practice field on Wednesday, and while he returned to throwing, the team was also quick to note that he is unlikely to play this Sunday. So, can Rattler navigate his way through a Chargers defense that has otherwise been stingy.
Los Angeles Chargers: Accepting A Franchise Shift
That’s a perfect segue into our focus on the LA side of this matchup. It has become very evident that the offseason changes have done exactly what we expected - cause a shift in the way this team needs to win games.
Long gone are the days of explosive offense with the likes of dual-threat RB Austin Ekeler and dynamic WR duo of Keenan Allen and Mike Williams. While QB Justin Herbert is still under center, he simply doesn’t have the weapons around him anymore.
Along with new head coach Jim Harbaugh also being more defensively-focused, the team needs to accept that low-scoring, grind-it-out games may be preferential for them.
Saints vs. Chargers Odds, Spreads, Total & Betting Lines
Despite both teams not being world-beaters, the Saints vs. Chargers odds still display a clear favorite for Sunday, and we have the latest lines at BetMGM Sportsbook for you here:
- Point Spread: New Orleans Saints +7.5 (-105) vs. Los Angeles Chargers -7.5 (-115)
- Money Line: New Orleans Saints (+280) vs. Los Angeles Chargers (-350)
- Game Total (Over/Under): Over 40.5 (-115) vs. Under 40.5 (-105)
Saints vs. Chargers Predictions: New Orleans +7.5 (-105 at BetMGM Sportsbook)
After having shared the Saints’ woes as of late, you may be surprised that the best bet from our Saints vs. Chargers picks is focused on the New Orleans point spread. However, with us getting them above the key number of seven, we’re happy to grab that value.
This primarily boils down to the fact that we don’t feel as though the Chargers should be favored by more than a touchdown over any team, even if they’re at home. Frankly, if there is one location in which home field matters the least, it’s Los Angeles.
We’ve even heard players say that it feels more like an away game at times, so that certainly isn’t a benefit for the Chargers. We’d also suggest considering the under after what we went through about the LA franchise shift. After all, the Chargers have scored more than 15 points just once in their past four games.
As most fans know, the lower scoring the game, the more it favors the underdog. That is especially true with a total as low as 40 and a point spread as high as seven! While LA may be able to keep Rattler and company in check, we don’t expect it to even take 20 points to keep this game within the point spread.
LA may very well get the win, but we’re still making the top pick from our Saints vs. Chargers predictions on New Orleans +7.5 (-105 at BetMGM Sportsbook).
Saints vs. Chargers Injury Report & Latest News
While Carr was the primary injury note for our Saints vs. Chargers predictions, we still have the full Thursday practice report for you below:
NO Saints:
- Derek Carr - DNP
- Nick Saldiveri - DNP
- Cedrick Wilson - DNP
- Lucas Patrick - LP
- Pete Werner - LP
- Khalen Saunders - LP
- Alvin Kamara - LP
- Juwan Johnson - LP
LA Chargers:
- Derius Davis - DNP
- Will Dissly - DNP
- Quentin Johnston - DNP
- Ladd McConkey - DNP
- Denzel Perryman - DNP
- Ja'Sir Taylor - LP
- Joey Bosa - LP
- DJ Chark - LP
- Kristian Fulton - LP
- Hayden Hurst - LP
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Player News
Dolphins signed No. 13 overall pick DT Kenneth Grant to a four-year contract.
ESPN’s Jeremy Fowler reports that Grant will sign his contract today. The former Michigan defensive tackle is expected to fill a major void left by Christian Wilkins, who left for the Raiders in the 2024 offseason. Grant totaled 32 tackles, three sacks, and seven TFLs in his final season at Michigan and excelled at stopping the run while also generating 27 pressures in his final season, per PFF.
Beat reporter John Hendrix reports that free agent WR Donovan Peoples-Jones is among the 16 players that the Saints will host for their rookie minicamp.
Peoples-Jones last played regular season snaps with the Lions back in 2023, when he caught 13-of-24 targets for 155 yards. He is highly unlikely to return to fantasy relevance at this point but could perhaps sign on as a special teams contributor.
Titans signed fourth-round pick WR Elic Ayomanor to a four-year contract.
Ayomanor will now begin learning behind Calvin Ridley. Although Ayomanor is unlikely to find a meaningful role in year one, dynasty managers should note his status as training camp gets underway this summer. The former Stanford receiver flashed big-play ability in his two college seasons.
Buccaneers signed seventh-round pick WR Tez Johnson to a four-year contract.
Johnson will serve as a rotational deep-threat option for Baker Mayfield. His thin frame (5'10/154) simply does not lend itself to the repeated hits one incurs in a full-time role. Johnson did earn 100-plus targets in his two seasons at Oregon, though. His big-play style make him a better fit in best ball for now, pending any major on-field breakthroughs.
Giants waived DT Casey Rogers.
Rogers was a 2024 undrafted free agent and logged 33 defensive snaps for the Giants in his rookie season. He is credited with zero tackles and/or sacks. He may find his way onto another roster as a practice squad option.
Vikings signed third-round pick WR Tai Felton to a four-year contract.
Felton is quietly in play to challenge Vikings No. 3 WR Jalen Nailor in training camp. Nailor (5'11/190) caught 28-of-42 targets for 414 yards and six touchdowns in his first season as a starter last year, with the latter category buoying his fantasy productivity. Felton (6'1/183), meanwhile, caught 96-of-143 targets for 1,119 yards and nine touchdowns while averaging 2.32 yards per route run in his final college season. Fantasy managers should monitor Felton’s training camp reports this summer, as he could have a matchup-based WR5 role if everything falls into place.