Cavaliers vs. Pacers Predictions, Picks & Odds: NBA on TNT, Today 4/10

The Cleveland Cavaliers take on the Indiana Pacers tonight, April 10, 2025, in a highly anticipated Eastern Conference matchup airing on TNT.
Thus, we have Cavaliers vs. Pacers predictions to present.
Cavaliers vs. Pacers Predictions for NBA on TNT, 4/10
With the regular season winding down, both teams' priority will be health entering the playoffs.
Our Cavaliers vs. Pacers picks look for the Pacers to come out hot and take the lead early against what could be the Cavaliers second unit.
Cleveland Cavaliers: Riding High With Championship Aspirations
The Cavaliers have been one of the standout teams in the NBA this season, boasting an impressive record and a roster firing on all cylinders. Donovan Mitchell continues to lead the charge, averaging over 24 points per game, while Darius Garland compliments him with crafty playmaking.
The frontcourt duo of Evan Mobley and Jarrett Allen provides defensive stability and rebounding prowess, making Cleveland a well-rounded contender. Coming off a strong stretch, the Cavaliers are focused on getting their second unit experience and possibly pull off an upset.
Indiana Pacers: High-Powered Offense Looking To Strike
The Indiana Pacers have relied on their explosive offense to stay competitive this season, with Tyrese Haliburton orchestrating the attack and players like Myles Turner and Buddy Hield providing scoring punch.
Despite some inconsistency, the Pacers have the firepower to challenge any team when their field goals are falling. Sitting in the middle of the Eastern Conference pack, Indiana is more or less set at the fourth position and will have home court advantage in the first round of the playoffs.
Cavaliers vs. Pacers Odds, Spreads, Total & Betting Lines
Here’s a look at the latest Cavaliers vs. Pacers odds for tonight’s matchup:
- Money Line: Cavaliers +310 | Pacers -395
- Spread: Cavaliers +9 (-110) | Pacers -9 (-110)
- Total (Over/Under): 232.5 (-110 both sides)
How To Watch Cavaliers vs. Pacers Tonight
To follow along with these Cavaliers vs. Pacers predictions, the game tips off at 7:30 p.m. ET from Rocket Mortgage FieldHouse in Cleveland, Ohio.
You can catch the action live on TNT, with streaming options available through the NBA League Pass, FuboTV, or the TNT app (subscription required). For those on the go, radio coverage is available on SiriusXM NBA Radio.
Cavaliers vs. Pacers Prediction: Indiana -9 (-110 on DraftKings)
The Cavaliers do not have one player prop available, and possibly their largest projected spread of the season. Despite a 34-6 record, the expectation in our Cavaliers vs. Pacers picks is for Indiana to come in and dominate this match. Their starters may not play the entire game, which would be a threat to this spread.
However, this could be their last full game too, and Head Coach Rick Carlisle has a full throttle philosophy to playing basketball. Regardless of which Pacers players are on the court, the gameplay will be fast with an emphasis on getting up and down the floor quickly. Our Cavaliers vs. Pacers predictions look for them to jump out to an early lead and cover the spread with their high-powered offense.
Cavaliers vs. Pacers Injury Report & Starting Lineup
Cleveland Cavaliers Injury Report:
- Donovan Mitchell (Out)
- Max Strus (Ou)
- Evan Mobley (Out)
- Darius Garland (Out)
Projected Cavaliers Starting Lineup:
- PG: Ty Jerome
- SG: Sam Merrill
- SF: De’Andre Hunter
- PF: Dean Wade
- C: Jarrett Allen
Indiana Pacers Injury Report:
- Ben Sheppard (Questionable)
Projected Pacers Starting Lineup:
- PG: Tyrese Haliburton
- SG: Andrew Nembhard
- SF: Aaron Nesmith
- PF: Pascal Siakam
- C: Myles Turner
Check for last-minute updates, as injuries could shift these lineups closer to tip-off.
How To Bet On Cavaliers vs. Pacers at DraftKings Sportsbook & Claim Your $150 Bonus
Ready to get in on the action? Here’s how to bet on Cavaliers vs. Pacers at DraftKings Sportsbook and claim a $150 bonus:
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No DraftKings promo code is required—just use this link to qualify. Bonus bets expire seven days after issuance, so use them wisely on this game or other NBA action this week. DraftKings offers competitive odds, a user-friendly interface, and fast payouts, making it a top choice for NBA betting.
Get your bets in before tip-off and enjoy our Cavaliers vs. Pacers predictions tonight!
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