Seahawks vs. 49ers Predictions, Picks & Odds: NFL Week 11, Sunday 11/17
There’s something special about divisional matchups. And they are even more special when they have meaningful implications. That’s exactly what we have here as the 5-4 San Francisco 49ers face off against the 4-5 Seattle Seahawks in their quest to catch the 6-4 Arizona Cardinals sitting atop the NFC West.
Both of these teams have gotten healthy in recent weeks making for an even better matchup. Coming out of the bye, DK Metcalf will return for the Seahawks while the 49ers recently got Christian McCaffrey and Jauan Jennings back. All that will need to be factored into our Week 11 Seahawks vs. Jaguars predictions for Week 11.
Even if you just want to see the Seahawks vs. 49ers odds and have Seahawks vs. 49ers picks of your own, don’t forget to scroll down at the end to see how you can scoop up a $1,500 BetMGM Sportsbook sign-up bonus!
Seahawks vs. 49ers Predictions For NFL Week 11, Sunday 11/17
This division “rivalry” has not been much of a rivalry in recent years. In fact, the 49ers have won the last 6 meetings including a playoff matchup following the 2022 season and their matchup in Seattle roughly a month ago. Seattle is hoping to turn those tides on the road this week in San Francisco.
The Seahawks also hope to end a tough stretch as they lost their last two games to the Los Angeles Rams and Buffalo Bills and have dropped three of the last four, including their meeting with the 49ers. The Niners on the flip side have won three of their last four win their lone loss coming against the undefeated Kansas City Chiefs.
Seattle Seahawks: The Return of DK Metcalf
It’s starting to look unlikely that Noah Fant will be ready for this week. But the return of DK Metcalf is a welcome sight for an offense that has been struggling without him. Ryan Grubbs loves his three WR sets and, as much as we love Jake Bobo, there are few who can compare to Metcalf. His presence elevates the entire offense. Even Kenneth Walker benefits as he scored six rushing touchdowns over his first five games but had his least efficient rushing games the last two weeks with no rushing touchdowns. A rising tide lifts all boats.
Seattle’s defense has been middle of the pack this season though they do have some key pieces. Tariq Woolen makes life difficult for opposing receivers while Derick Hall and Boye Mafe have done a decent job of getting after the quarterback so far.
San Francisco 49ers: The Christian McCaffrey Show
Jordan Mason did a commendable job filling in for Christian McCaffrey. But one spot where he doesn’t offer as much is the pass game. Mason had only 12 targets over his 9 starts while CMC, in his first game back, garnered 7 targets. With Jauan Jennings in the Brandon Aiyuk role and Ricky Pearsall taking over the slot, this team is as close to 100% as they’re going to be on offense.
On defense, the 49ers have smothered the pass, especially for tight ends over the middle with Fred Warner and De’Vondre Campbell. They’ve actually ranked 20th in DVOA against the run per FTN Fantasy so they do leave something to be desired up front. Overall they are still one of the league's best defenses. Their top corner, Charvarius Ward, has been away from the team for two weeks after the unfortunate passing of his two year old daughter. He won’t play this week but is expected to return in the near future.
Seahawks vs. 49ers Odds, Spreads, Total & Betting Lines
As promised, the latest Seahawks vs. 49ers odds can be found below courtesy of BetMGM Sportsbook:
- Point Spread: Seattle Seahawks +6.5 (-110) vs. San Francisco 49ers +6.5 (-110)
- Money Line: Seattle Seahawks (+240) vs. San Francisco 49ers (-300)
- Game Total (Over/Under): Over 48 (-110) vs. Under 48 (-110)
Seahawks vs. 49ers: Game Total Over 48 Points (-110 at BetMGM Sportsbook)
It’s completely understandable that Charvarius Ward would have as much time as he needs before he returns to the team. Some things are bigger than football. His absence coinciding with the return of DK Metcalf does put the 49ers in a tough spot. Metcalf has been the missing piece to opening up this offense - the 49ers haven’t been stellar against the run and now they’ll be without their top corner.
On the flip side, the 49ers are now fully healthy with Christian McCaffrey, Jauan Jennings, and Ricky Pearsall all back. We watched them hang 36 on the Seahawks last time they played despite Brandon Aiyuk only have 2 catches for 37 yards. Jauan Jennings so more than capable in that role and CMC is the best running back in the NFL so I don’t expect them to struggle this week. I’m going with the over here.
Seahawks vs. 49ers Injury Report & Latest News
Finally, let’s take a quick look at the projected starting lineups for both teams heading into tonight’s matchup:
SEA Seahawks
- TE Noah Fant - Out
- TE Brady Russell - Out
- C Connor Williams - Out
SF 49ers
- DT Kevin Givens - Out
- CB Charvarius Ward - Out
- P Mitch Wishnowky - Out
- CB Darrel Luter Jr - Doubtful
- DE Nick Bosa - Questionable
- TE George Kittle - Questionable
- OT Trent Williams - Questionable
- G Jon Feliciano - Questionable
- G Aaron Banks - Questionable
- DE Yetur Gross-Matos - Questionable
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Player News
Packers signed WR Bo Melton, RB Emanuel Wilson, and P Daniel Whelan to their exclusive rights free agent tenders.
Melton caught on with the Packers in 2023, totaling 16 receptions for 218 yards and a touchdown in five games. He added eight receptions for 91 yards in 17 games last season. Melton will continue to be a depth piece in an already-deep Packers wide receiver room. Wilson has also been with the Packers for two seasons and rushed for 502 yards and four touchdowns as Josh Jacobs’ immediate backup last season. He will compete with MarShawn Lloyd for that role again. Whelan is the team’s punter and will be back for 2025. All three signed their exclusive rights free agent tender and will essentially be on one-year contracts this season.
Seahawks re-signed Johnathan Hankins to a one-year contract.
Hankins hasn’t had a PFF run defense grade above 52.4 since 2020 and is primarily called on to play early downs. He turned 33 in March. He’ll be a complimentary piece behind Jarran Reed and Byron Murphy II if he makes the roster out of training camp.
Chargers placed the UFA tender on RB J.K. Dobbins.
This gives the Chargers exclusive negotiating rights if he does not sign with a team by July 22 or the first 2025 NFL training camp opens, whichever comes first. The tag is mainly useful for compensatory pick reasons as Dobbins will still count towards Los Angeles’ haul in the formula if signed before then. The Chargers currently do not project to add a pick in 2026 per Over The Cap’s Nick Korte.
49ers signed OT D.J. Humphries.
Humphries played in only two games for the Chiefs last year as he spent most of the season rehabbing a late 2023 torn ACL on his own. He wasn’t appreciably good in either of those games, but he was rusty and does have a history of better than that. Entering his age-32 season for the 49ers, he’ll probably be trying to win the right tackle job opposite Trent Williams in training camp.
Patriots released LS Joe Cardona.
The team selected his replacement, Julian Ashby, in the seventh round of the draft. This snapper of balls who are longer than usual is only 33, and it’s possible he picks up his career elsewhere. There aren’t too many remaining Patriots Regimes in the wild in 2025, but Nick Caserio does still run the Texans and they let Jon Weeks walk this offseason so that’s one speculative fit.
NewOrleans.Football’s Nick Underhill said he would be “flabbergasted” if Derek Carr played for the Saints this year.
“I would have trouble understanding why you would allow that to happen, you’re trying to build a new culture, you can’t let that guy ... you just got a rookie QB, this is the example you’re going to give him,” Underhill continued. Both Underhill and Mike Triplett believe Tyler Shough will be starting for the Saints in Week 1, with Underhill saying he had “80 percent or higher odds to start 80 percent of the games this year.” Shough would be an uninspiring superflex pick, perhaps a QB3, but given how things have played out with Carr over the past months it sure doesn’t seem like the Saints have a reason to want to continue this relationship. Mickey Loomis literally asked reporters to stop asking him Carr questions at his pre-draft press conference.