Yet again, the Detroit Lions are coming off an absolute dominant performance and will be looking to continue their hot streak in relatively nearby Indianapolis against the Colts. As we prepare for this NFC vs. AFC clash, we’ve broken down our Lions vs. Colts predictions and top pick for you.

Whether you end up rolling with the best bet from our Lions vs. Colts picks or see something else that catches your eye, we’ll also provide you with a huge $1,500 BetMGM Sportsbook new user offer to enjoy using any betting market!

 

 

 

Lions vs. Colts Predictions For NFL Week 12, Sunday 11/24

Overall Lions vs. Colts predictions? Detroit winning yet again. As great as it would be for things to be that easy, that is far from the case. Any team can beat any other team on any given Sunday, but we don’t see Indy getting in the way of this Dan Campbell-led freight train.

The highest total a team has reached this season is 52, which has been the Lions - twice. That came in a similar situation last Sunday against an AFC South team. While they will be on the road this time around, they’ll be back in a dome, so they can treat it just like Ford Field if they’d like.

Detroit actually isn’t as big of a favorite as they were last week despite a 52-6 victory, and we’re going to use that to our advantage for the top pick from our Lions vs. Colts predictions.
 

 

 

Detroit Lions: Roaring Through The NFC

Before we fully get into our favorite approach for Lions vs. Colts picks, let’s outline each team in this interconference clash. It’s one that may end up being between two playoff teams, but it’s certainly not Detroit that is leaving that in question.

There was speculation as to whether or not they could be true Super Bowl contenders after superstar pass rusher Aidan Hutchinson went down for the season, but they quickly silenced those doubts. Sitting at 9-1 and on an eight-game winning streak, they are the clear favorites to represent the NFC in the Super Bowl this February.
 

 

 

Indianapolis Colts: Richardson Rolls

While the Colts have work to do for their right to get into the postseason, a win here would get them back to .500 with a 6-6 record. It hasn’t been without drama, though - second-year QB Anthony Richardson was benched in lieu of 39-year-old QB Joe Flacco.

After back-to-back losses led by Flacco, the team once again turned to Richardson this past Sunday, who absolutely showed why he was drafted with the #4 overall pick two offseasons ago. He ran for two scores in a very close 28-27 win over the New York Jets, which led to them firing their general manager on Tuesday morning.
 

 

 

Lions vs. Colts Odds, Spreads, Total & Betting Lines

Keep the above score in mind as we start breaking down the best bet from our Lions vs. Colts predictions, but first, the latest Lions vs. Colts odds at BetMGM Sportsbook:

 

 

Lions vs. Colts Teaser: Detroit -1.5 & Over 44.5 (-120 at BetMGM Sportsbook)

As you can see, our favorite Lions vs. Colts picks come in the form of a teaser. This is a way for us to modify the lines in our favor, and while they both need to come to fruition, we are supremely confident in them doing so.

We saw the Lions as 11-point favorites on the road last weekend, and boy did they cover. They routed the Jacksonville Jaguars to the tune of 52-6, and it wasn’t just the final score that has us believing that they will do the same this weekend.

Head coach Dan Campbell never let his foot off the gas. Even when they were up 42-6, he had all his starters in the game, AND threw the ball for explosive plays. Whether it’s to pad QB Jared Goff’s stats to build his MVP resume or just to instill fear in other teams, the fact remains that Campbell is making a statement.

Superstar WR Amon-Ra St. Brown was the touchdown scorer in the fourth quarter to make it 49-6, so they truly never let up. With the Colts allowing the seventh-most passing yards per game, there’s no reason for us to think that Goff won’t have another MVP-caliber performance in Indy.

The Colts have also proven that they love these shootouts, as we noted to remember their 28-27 win just this past weekend. When they played Detroit’s opponent from last Sunday - the Jags - it was yet another shootout with a 37-34 final score. Even if Indy isn’t able to exploit a weak Lions secondary (sixth-most passing yards per game), Detroit has proven multiple times that they can cover the total themselves.

Along with Campbell’s crew being 8-2 against the spread this season, we love targeting Detroit -1.5 and over 44.5 points (-120 at BetMGM Sportsbook) as our best Lions vs. Colts picks.
 

 

 

Lions vs. Colts Injury Report & Latest News

We know that Aidan Hutchinson won’t be seeing the field again this season, and we’ve already seen Richardson return from his injury and benching. Other noteworthy players that often find themselves dealing with ailments are Colts RB Jonathan Taylor and Lions RB Jahmyr Gibbs. So, be sure to always be in the know with the latest NFL injury report from Fantasy Alarm.
 

 

 

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Even if teasers aren’t your cup of tea and you want to take a different approach from our Lions vs. Colts predictions, here’s how you can do so with $1,500 worth of first-bet protection at BetMGM:

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