After sharing our best NFL player prop picks for the Thanksgiving and Black Friday action, we’ve got another prime time game to enjoy with Sunday Night Football between the San Francisco 49ers and Buffalo Bills. So, of course, we also have our best NFL SNF player prop picks for you!

To add some additional value to our 49ers vs. Bills player props, we’ll also take you through a fantastic FanDuel Sportsbook sign up bonus for multiple rewards!

 

 

 

Best NFL Sunday Night Football Player Prop Picks

There is no doubt that NFL SNF player prop picks will be a popular approach for this matchup with how many variables and moving parts are involved. What was once one of the most likely Super Bowl matchups now has one of the most significant point spreads of the entire Week 13 slate.

Not only do many fans prefer not to target such markets, but there are several key injuries at play. They are primarily with the 49ers - QB Brock Purdy, OT Trent Williams AND DE Nick Bosa. Even the Bills have concerns with TE Dalton Kincaid and WR Keon Coleman. However, understanding how these injuries affect the rest of the team can make NFL SNF player prop picks even more valuable.

We’re going to be focusing on the QBs in this NFC vs. AFC clash, so let’s break down our best 49ers vs. Bills player props.
 

 

 

49ers vs. Bills Player Props: Josh Allen Anytime TD Scorer (+135 at FanDuel Sportsbook)

First up for our NFL SNF player prop picks is the QB with no question marks heading into this matchup. Not only is that the case for Buffalo QB Josh Allen, but he’s also one of the MVP frontrunners!

As we’ve all seen by now, that’s thanks to his dominance both with arguably the strongest arm in the NFL and his incredible running ability. The latter is what we’re focused on to provide you with some plus-money odds.

Firstly, if we don’t see Bosa back on the field, that would certainly be ideal, but even if he is back, the 49ers defense simply hasn’t been what we’ve seen the past few seasons. Specifically, they’ve been allowing teams to find the endzone on the ground on a regular basis. They’ve done so in each of their past six games, including multiple with 2+ rushing TDs allowed.

That also includes allowing the Dallas Cowboys to score a rushing touchdown, who has the worst run offense in the NFL. While Allen may not technically be an RB, he’s still one of the best rushers in the league. Therefore, we’re starting our NFL SNF player prop picks with Josh Allen to score an anytime touchdown (+135 at BetMGM Sportsbook).
 

 

 

49ers vs. Bills Player Prop Bets: Brock Purdy Over 0.5 Interceptions at FanDuel Sportsbook

Next up for our NFL SNF player prop picks is the other QB in this matchup. Now, we mentioned the Purdy injury concern, and while he was limited at practice this week, the hope is for him to be back on the field for such a crucial game.

If for some reason it isn’t Purdy, we’d still suggest the same addition to our 49ers vs. Bill player props, as the Buffalo defense has simply been fantastic in this department. There will likely be some extra juice with a backup QB, but it should be worth the squeeze.

The Bills’ secondary was looking questionable given that they lost nearly the entire unit this offseason, but they have picked up right where they left off. Their 13 interceptions this season are the fourth-most in the NFL, and let’s not forget about another one of San Francisco’s injury concerns.

Star LT Trent Williams is also questionable, which means more pressure on whichever QB is under center. Of course, that leads to forced quicker throws and more likely turnover opportunities. While we need to monitor the line for this portion of our NFL SNF player prop picks, we still love Brock Purdy to throw an interception with expected odds of around -120 at FanDuel Sportsbook.
 

 

 

Sunday Night Football Player Props At FanDuel Sportsbook

To add on to our best NFL SNF player prop picks, here are some other popular 49ers vs. Bills player props at FanDuel Sportsbook:

Passing Yards:

  • Josh Allen: Over 228.5 (-114) vs. Under 228.5 (-114)

Rushing Yards:

Receiving Yards:

 

 

 

How To Bet On NFL Week 13 Sunday Night Football at FanDuel Sportsbook & Claim Your $150+ Bonus

We also promised a FanDuel Sportsbook sign up bonus to go along with our best NFL SNF player prop picks, and here’s how it works:

  1. Sign up here for a new FanDuel account
  2. Make a first-time deposit of $10 or more
  3. Wager $5 or more on any betting market

Then, as long as that $5+ qualifying wager wins, you’ll receive $150 in bonus bets PLUS your normal payout! Additionally, there is a guaranteed bonus, which is three free months of NBA League Pass. That means value far beyond just Sunday Night Football and the NFL, so be sure to join FanDuel today.