NBA Best Bets Today, 4/22: Picks, Predictions & Player Props - Tuesday

Isaiah Stewart was a late scratch for the Detroit Pistons, who rallied around Jalen Duren and his double double performance. He easily earned over 10.5 rebounds with Stewart out of the lineup. The Denver Nuggets and Los Angeles Clippers put up another outstanding game that went to the last field goal attempt.
Despite committing 20 turnovers, and missing eight free throws, Denver only lost by three points. Kawhi Leonard put on one of the best performances as a Los Angeles Clipper, as he easily worked his way down to his favorite spots on the court. He went on to score 39 points with 15 of 19 field goals made.
Russell Westbrook came in and earned 2 rebounds in his first minutes but could not get off his rebounding hook late in the game, proving detrimental to our NBA predictions. He was still a factor, making two three-point field goals late in the game.
NBA Picks, Predictions & Best Bets Today, 4/22
There are three games across the Association tonight, and there will be a wager from each match for our NBA best bets today. For a more in depth look at Memphis Grizzlies versus Oklahoma City Thunder check out the article under the NBA betting tab.
The first of our NBA best bets today comes from the Milwaukee Bucks versus Indiana Pacers match.
Bucks vs. Pacers Prediction: Brook Lopez Over 4.5 Rebounds (+115 on BetMGM) *BET OF THE NIGHT
The Pacers host the Bucks for game 2 at Gainbridge Fieldhouse, and the Bucks are welcoming their teammate with arms wide open. Damian Lillard has been cleared to return action, and will play tonight. The Indiana Pacers won game one in dominating fashion, 117 - 98. The spread is currently -3.5 in Indiana’s favor, as this game is expected to be a much closer match.
One player that can contribute to a win is the longtime veteran, Brook Lopez. Although his minutes have been reduced he is effective when on the court. He had just 9 points and 4 rebounds in 21 minutes in game one. If this game is competitive Lopez should play closer to his season average of 31.8 minutes per game.
He is erratic with his rebounding, and teammate Giannis Antetokounmpo is one of the best rebounders in the league, but Lopez is more than capable of earning 5 rebounds. In fact it is his season average, 5.0 rebounds per game, and he has recorded 5 or more rebounds in three of his last six matches.
The entire team should be playing with max effort to avoid going down 0-2, put a unit on Lopez to earn his average, and for those new to BetMGM, make sure to take advantage of Fantasy Alarm’s offer for Bonus money.
Grizzlies vs. Thunder Prediction: Total Under 228.5 (-110 on Bet365)
The Memphis Grizzlies look to improve on their last performance at the Paycom Center but are better rested for this match. Jaren Jackson and Zach Edey will have to improve on their scoring as they each only scored four points. Marvin Bagley cannot be the highest scorer for the Grizzlies if they are going to have a chance to win the game.
Ja Morant is an elite scorer and will be much better tonight. They will also need to play much better defense as it takes awful offense and a lack of defense to lose by 51 points. As great as the Oklahoma City Thunder are offensively, their defense is what allowed them to win by such a large margin.
Shai Gilgeous-Alexander will be pressed and double-teamed once again, and the role players of the Thunder may not have the same success they did in game one. With the Grizzlies expected to be better offensively, the Thunder are expected to be worse offensively. Both teams should play with a defensive mindset in game two.
Put a unit on the total being under 228.5 points as that is a high total for the NBA playoffs. For those that are new to Bet365, make sure to take advantage of Fantasy Alarm’s promotional offer. Place this portion of our NBA best bets today and earn bonus cash!
Best NBA Prop Bets & Other Picks Today, 4/22
The last of our NBA best bets today comes from Crypto.com Arena and could be the best game of the night.
Timberwolves vs. Lakers Prediction: Naz Reid Over 11.5 Points (-130 on DraftKings)
The Minnesota Timberwolves absolutely embarrassed the Los Angeles Lakers in game one, with a 117 - 95 upset victory. The game was essentially over before the second half, as Minnesota’s tenacious defense kept the Lakers in check throughout three quarters.
Heading into tonight's match the Lakers are -5.5 point favorites on the spread, and the expectation is for a bounce back game from Los Angeles. Luka Doncic and LeBron James know what’s at stake, and that a game two loss at home would be disastrous for their championship chances. The Lakers have had two days to rest and take advantage of game tape for roster and scheme adjustments, but so has Minnesota.
The Timberwolves exposed the Lakers with Naz Reid who scored 23 points and was five from nine behind the arc. Reid is a game changer, and it is due to him that Minnesota felt comfortable trading away Karl-Anthony Towns. Reid played 31 minutes in game one, and could be around thirty again as the Lakers have no answer for covering him while stopping Anthony Edwards. Reid is too big to stop down low, and they have no one that can defend him from the perimeter.
He averages 14.2 points per game and should have no problems scoring 12 tonight. Put a unit on DraftKings and for those new to the sportsbook, remember to take advantage of the promotional offer from Fantasy Alarm.
Get $150 in Bonus Bets Today At Bet365 Sportsbook When You Sign Up
Ready to jump into the action? New users can score a fantastic deal with Bet365 Sportsbook without even needing a Bet365 promo code. Sign up today, place a $5 wager, and instantly receive $150 in bonus bets—win or lose! It’s one of the best offers out there, giving you extra firepower to follow our NBA picks today.
Whether you’re fading or following our NBA best bets today, this promo reduces the risk and boosts your potential payout. Head to Bet365 now to claim your $150 in bonus bets and get in on the NBA excitement! With these NBA predictions and options in hand, you’re set for a profitable night.
Bet Smart, Be Lucky - Iggy
*All NBA odds accurate at time of writing and NBA best bets today to be placed at 1 unit unless specified otherwise
Looking for more NBA picks and strategy? From props to playoff insights, we’ve got you covered.
Fantasy Alarm is your go-to for expert NBA coverage. Join the conversation in our Discord and don’t miss our breakdowns on YouTube and X.