Guardians vs. Orioles Predictions, Picks, Odds & Starting Pitchers: Today, 4/15

After both the Cleveland Guardians and Baltimore Orioles had divisional series over the weekend and a day off on Monday, they now begin against one another. Although we didn’t end up seeing this matchup play out in last year’s playoffs, this series opener will still be featured on TBS, and we’ve got our Guardians vs. Orioles predictions for you.
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Guardians vs. Orioles Predictions For MLB on TBS, 4/15
Through the first three weeks of the season, it can be argued that the O’s are among the biggest disappointments thus far. Of course, it’s a long season for fans to feel too bad about things, but sitting at the very bottom of the AL East is not what they expected at this point.
Baltimore had a great chance to get back to a game within .500 on Sunday, but an eighth inning collapse against the Toronto Blue Jays allowed them to extend the game to extra innings, where they ultimately won it. That came after scoring in all four innings to begin the game and six runs in total across the first six innings.
A similar story was told in Cleveland, as the Guardians had an early 2-0 lead in the second inning, but still fell to the Kansas City Royals. With less than stellar performances for both teams last time out, who can we trust for our Guardians vs. Orioles predictions today?
Cleveland Guardians: No Place Like Home
Despite that aforementioned loss to the Royals on Sunday, the Guardians have still loved playing at Progressive Field in Cleveland. Prior to that defeat, they were among just a few teams that were undefeated at home this year, and there is now just one - the San Diego Padres.
However, the Guardians will be leaving that 5-1 home record to head to Baltimore for this matchup. Although that’s the case, they shouldn’t be extremely upset about things. Even with that strong home record, they’ve hit just five homers at Progressive Field, and Camden Yards in Charm City is great for those.
Baltimore Orioles: Starting Pitching Struggles
Speaking of hitting bombs in Baltimore, the O’s starting rotation has been even greater for hitters in that regard. Their rotation has been their biggest issue even during this franchise turnaround the past few seasons, and it’s continued this year; they have the absolute worst starting pitching ERA in the league.
That will be on full display with Charlie Morton taking the mound. The former Braves is known for his curveball, but it hasn’t been fooling anyone this season. He’s had three starts for his new team, and he’s 0-3 with an 8.78 ERA. While he did have a double-digit strikeout game, that’s just some individual glory for himself.
How To Watch Guardians vs. Orioles Today
To get you fully prepared for tonight’s series opener in Baltimore, here is how to watch Guardians vs. Orioles today:
- Where: Orioles Stadium at Camden Yards in Baltimore, MD
- When: 7:05 PM ET on 4/15
- Watch on TV: TBS
- Where to stream: MLB.TV
Guardians vs. Orioles Odds, Spreads, Total & Betting Lines
For more info regarding the matchup overall as we transition into our best bet, here are the latest Guardians vs. Orioles odds:
- Run Line: Cleveland Guardians -1.5 (+140) vs. Baltimore Orioles +1.5 (-165)
- Money Line: Cleveland Guardians (-115) vs. Baltimore Orioles (-105)
- Game Total (Over/Under): Over 9 (-115) vs. Under 9 (-105)
Guardians vs. Orioles Best Bet: Over 9 Runs (Target Some Player Picks At PrizePicks)
As we mentioned at the start, these teams didn’t end up meeting in the 2024 playoffs, but they did face one another seven times. The Guardians edged out that season series 4-3, and they had the same record in terms of covering the run line.
That said, we’re going to focus on a different trend, which were high-scoring games. Five of those seven matchups went over the total, including each of the most recent four games. While we’re well aware that these games are from last season, given what we broke down about the O’s pitching, there’s no reason to expect anything different this time around.
We wouldn’t be surprised if Charlie Morton gave up the entire total himself tonight, and even if he doesn’t, this is a spot where Baltimore’s lineup can “re-prove” themselves so to speak. Last season, the O’s were among the best in terms of hitting lefties with a .750 OPS, and they’ll be facing one tonight in Cleveland’s Logan Allen.
He’s not exactly set up for success with Camden Yards having moved in the left field fence this offseason, making it even more of a hitter’s park. Even without that factor, the O’s faced Logan Allen last year and torched him to the tune of six earned runs on nine hits in just three innings of work.
With that type of track record and the environment overall, we’re locking in the best bet from our Guardians vs. Orioles predictions on the over 9 runs (PrizePicks has player projections to target as well).
Guardians vs. Orioles Injury Report & Starting Pitchers
The Orioles pitching woes have been so frustrating since the hype around lefty John Means died with his consistent injuries, and now as a member of Cleveland, guess what? He’s on the IL.
As for other Guardians vs. Orioles injury news, Baltimore is even more looking forward to Grayson Rodriguez getting back on the bump after having to place starter Zach Eflin on the 15-day IL.
Given that the best bet from our Guardians vs. Orioles predictions was focused on a high-scoring game, we’ve noted the pitching duel already, but you can also see the Guardians vs. Orioles starters for today here
- Cleveland Guardians starting pitcher today: Logan Allen (0-1, 3.60 ERA)
- Baltimore Orioles starting pitcher today: Charlie Morton (0-3, 8.78 ERA)
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