Cardinals vs. Packers Predictions, Picks & Odds: NFL Week 6, Sunday 10/13

After taking on an NFC West team on the road last Sunday, the Green Bay Packers get to host one this Sunday with the Arizona Cardinals coming to town. Both teams are coming off one-score victories, so they’ll be looking to roll over the momentum. Only one can prevail, and we’ve broken down our best Cardinals vs. Packers predictions for you below.
Not only will we have a best bet from our Cardinals vs. Packers picks, but we’ll also take you through a guaranteed $200 DraftKings Sportsbook welcome promotion!
Cardinals vs. Packers Predictions For NFL Week 6, Sunday 10/13
If you’re ready for a game that looks like a color rush matchup, this one's for you. With the green and gold of the Packers at home and bright red of the Cards, you’ll be sure to have your senses heightened.
That will likely get enhanced even more audibly with the tough running of Arizona RB James Conner and Green Bay RB Josh Jacobs - two of the most physical runners in the league. With these two old school backs, we expect a heavy dose of the ground game from both sides.
Generally, that correlates to a low-scoring game, but with how these teams matchup, we actually have one of the highest totals on the board. Keep that in mind as we work our way to the best bet from our Cardinals vs. Packers predictions.
Arizona Cardinals: Riding The Rollercoaster
Arizona may be thought of as a flat desert by many, but thanks to the Cards, it’s been more like an amusement park this season. After nearly knocking off the Buffalo Bills to open the season, they then blasted the Los Angeles Rams 41-10, only to lose the following week scoring just 13 points.
Following that was an embarrassing 42-14 loss at home to the Washington Commanders, but then this past Sunday, they knocked off the San Francisco 49ers on the road! As you can see, getting a good read on this team has been rough, but they have some trends along the way that we’re locked in on.
Green Bay Packers: Dealing With The Drama
So, QB Aaron Rodgers leaves town, but there’s still drama in Green Bay? Well, it’s no longer with QB Jordan Love, but rather, his weapons. With WR Christian Watson dealing with injury, it could have been time for WR Romeo Doubs to shine if he could get back to 100% healthy.
Instead, he decided to just not show up to practice prior to last week’s contest, which led to the team suspending him. The Pack still went on to defeat an injury-riddled Rams team, but remember, we already shared that the Cards smacked LA 41-10 themselves.
Cardinals vs. Packers Odds, Spreads, Total & Betting Lines
Below, you’ll see the latest Cardinals vs. Packers odds at DraftKings Sportsbook. While we didn’t use the standard markets for the best bet from our Cardinals vs. Packers predictions, it’s only a slight variation.
- Point Spread: Arizona Cardinals +5 (-105) vs. Green Bay Packers -5 (-115)
- Money Line: Arizona Cardinals (+195) vs. Green Bay Packers (-238)
- Game Total (Over/Under): Over 49.5 (-110) vs. Under 49.5 (-110)
Cardinals vs. Packers Predictions: First Half Over 24.5 Points (-108 at DraftKings Sportsbook)
You may have saw something like this coming for the best bet from our Cardinals vs. Packers picks given everything we’ve gone through. Firstly, you’ve seen that the Cards have enjoyed their high-scoring games, whether it’s them lighting up the scoreboard or the opponent.
They both scored over 40 points this season in a single game and allowed the same, and we aren’t concerned with which team does what - we just need at least 25 points on the board at the half.
We’re also isolating the first half because these teams have been great for bettors in that regard. Starting with Arizona, they’ve scored the ninth-most first-half points (13.6/game), while allowing the fifth-most (14.6/game). As for Green Bay, they score 13.2 first-half points per game while allowing 13 first-half points per game.
Both teams having winning records for overs in general as well, but we’re going to stick with just the first two quarters, making the best bet from our Cardinals vs. Packers predictions on the over 24.5 points in the first half (-108 at DraftKings Sportsbook).
Cardinals vs. Packers Injury Report & Latest News
We’ve seen Love back in action since his early-season injury, but GB certainly has guys to keep an eye on still. Here’s the Thursday practice report for both teams:
ARI Cardinals:
- DL Darius Robinson - DNP
- OL Kelvin Beachum - LP
- OL Evan Brown - LP
- LB Jesse Luketa - LP
- DL Bilal Nichols - LP
- K Matt Prater - LP
- CB Garrett Williams - LP
- WR Zay Jones - LP
GB Packers:
- DL Devonte Wyatt - DNP
- TE Luke Musgrave - DNP
- WR Christian Watson - LP
- CB Jaire Alexander - LP
- DT Kenny Clark - LP
- LB Edgerrin Cooper - LP
- DL Jonathan Ford - LP
- LG Elgton Jenkins - LP
- TE Tucker Kraft - LP
- G Jordan Morgan - LP
- CB Carrington Valentine - LP
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Player News
Beat reporter Scott Bair reports that Bears DC Dennis Allen asked slot CB Kyler Gordon to learn a second position, either on the perimeter or at safety.
The Bears’ previous coaching staff spent two seasons trying this experiment before allowing Gordon to blossom in a full-time slot- and box-coverage role last season. Perhaps, Allen can succeed where others have failed. His intent is to “find some more playing time” for Gordon, which is understandable given Gordon’s significant on-field impact last year.
Bills signed CB Tre’Davious White, formerly of the Ravens, to a one-year, $6.8 million contract.
White, now 30 years old, returns to the team that drafted him in the 2017 NFL Draft’s first round. White was a force to be reckoned with early in his career, but a 2021 ACL tear and a 2023 Achilles tendon rupture have reduced his play quality. White will now compete for the Bills’ No. 2 perimeter role.
Bills waived TE Armani Rogers.
This is unfortunate. Rogers recently ruptured his Achilles tendon for the second time in three years. He showed promise as a 2022 rookie, earning a 65.3 PFF receiving grade and a 68.0 PFF run-blocking grade, but the injuries are taking their toll. The Bills also released DT Branson Deen.
Titans waived OT Nicholas Petit-Frere.
The team signed C Sam Mustipher and OT Oli Udoh in corresponding moves. Petit-Frere failed to meet expectations after the Titans spent a third-round pick on him in 2022, allowing 35-plus quarterback pressures in 2-of-3 NFL seasons.
Cowboys signed OL Hakeem Adeniji, formerly of the Browns, to a contract.
The former 2020 sixth-round pick last took regular season snaps in 2022. Adeniji spent the 2023 season serving as a part-time special teams player, and although he was technically on the Browns’ 2024 roster, he missed the full season on injured reserve. Adeniji will likely handle a deep-backup/special teams role in Dallas this year.
Free agent QB Aaron Rodgers said on The Pat McAfee Show that he is currently focusing on matters in his personal life while mulling his future in the NFL.
In a wide-ranging discussion with McAfee, Rodgers said that he is still contemplating whether to play in 2025 or retire this offseason, though he has settled on a $10 million asking price, should he choose to stick around. Rodgers repeatedly, yet ambiguously, emphasized that caring for troubled members of his “inner circle” has been his offseason priority. Rodgers spoke positively of his recent visit with the Steelers, praising head coach Mike Tomlin, OC Arthur Smith, GM Omar Khan, QB coach Tom Arth and WR DK Metcalf, whom he called “a specimen” and a “great dude.” Rodgers downplayed reports about pitching Vikings head coach Kevin O’Connell on a union, saying much ado has been made about two old “friends” remaining in regular contact. The free agent QB also notably complimented Giants head coach Brian Daboll’s “beautiful football mind” but kept Giants-talk relatively succinct. Rodgers made clear that the rapidly approaching 2025 NFL Draft will have no bearing on his decision-making timeline, and he understands if the Steelers determine that they must move on without him. In short, it appears as though Rodgers will either sign with the Steelers or move on from football. The enigmatic quarterback gave few indications as to which direction he is leaning.