Giants vs. Browns Predictions, Picks & Odds: NFL Week 3, Sunday 9/22

Two teams that had disappointing Week 1 performances were the New York Giants and Cleveland Browns, both losing by 16+ points. As for Week 2, only one of them - the Browns - bounced back with a win. New York fell to 0-2 in historic fashion, which we’ll share with you as we get into our best Giants vs. Browns predictions!
After we progress into the best bet from our Giants vs. Browns picks, we’ll also provide you with the details regarding a guaranteed $200+ FanDuel Sportsbook sign up bonus!
Giants vs. Browns Predictions For Week 3, Sunday 9/22
Entering the season, there’s no denying that the Giants and Browns had different expectations placed on them. New York has fully looked the part of a non-playoff team, while Cleveland is trying to prove oddsmakers right by getting back to the postseason.
Neither team has been inspiring, especially on the offensive side of the ball. The G-Men were at least able to force the Washington Commanders to the brink in a 21-18 loss, but it was ugly nonetheless. Similarly, the Browns squeaked out an 18-13 win over the Jacksonville Jaguars, so perhaps the change of scenery was what they needed.
They’ll be back in front of the Dawg Pound this Sunday in what is projected to be a low-scoring game.
New York Giants: Making NFL History
As promised, the Giants made history with their loss to the Commanders. Washington needed a field goal as time expired to grab the victory, and in fact, field goals were all they needed. The Commanders’ seven field goals were what drove this historic matchup.
New York losing a game while scoring three touchdowns and allowing none was just the second time in NFL history. So, while they may not have been the first and only team to do it, the rarity of it is still staggering. In such games, the teams to score the three touchdowns were a whopping 1,294-1! It looks as though it could be a long season for Brian Daboll’s guys.
Cleveland Browns: Curing The Watson Woes?
After the Browns were all but crushed by the Dallas Cowboys on their home turf in Week 1, it was as if the season was already lost. Well, at least the faith in QB Deshaun Watson was already lost.
The criticism was that Watson and head coach Kevin Stefanski weren’t on the same page from a play-calling perspective, and truthfully, the offense’s 18 points didn’t quite put that speculation to bed. Watson going 22-for-34 could have certainly been worse, but it was how much better he looked running the ball that was the vast improvement. New York just had to deal with Washington QB Jayden Daniels doing just that as well, so we aren’t surprised to see the Giants vs. Browns odds having Cleveland as significant favorites.
Giants vs. Browns Odds, Spreads, Total & Betting Lines
Speaking of the Giants vs. Browns odds, here are the latest lines courtesy of FanDuel Sportsbook before we dive into the best bet from our Giants vs. Browns predictions:
- Point Spread: New York Giants +6.5 (-105) vs. Cleveland Browns -6.5 (-115)
- Money Line: New York Giants (+245) vs. Cleveland Browns (-300)
- Game Total (Over/Under): Over 38.5 (-110) vs. Under 38.5 (-110)
Giants vs. Browns Predictions: Under 38.5 Points (-110 at FanDuel Sportsbook)
Yes, it’s a very low total. No, we aren’t worried. We’re still focusing on the under with our Giants vs. Browns predictions, and for good reason. First and foremost, you already saw the scores from these teams in their Week 2 matchups.
They both put up just 18 points and in Week 1, New York scored just six points, while Cleveland scored just 17. Truthfully, that included a garbage time touchdown, so it was more like a 10-point performance. Now, the Giants defense certainly isn’t the 2000 Baltimore Ravens, but they at least demonstrated a bend-don’t-break ability last Sunday.
Losing to seven field goals is certainly not a positive, but at least they tightened up where it matters most - in the red zone. As for Cleveland, their defense has been regarded as their best unit, so there isn’t nearly as much to convince in that regard. That’s even more true facing a Giants offense that lacks any sort of superstar with RB Saquon Barkley now in Philly.
So, if you love defensive, grind-the-clock football, this game is for you, which is why the best bet from our Giants vs. Browns predictions is under 38.5 points (-110 at FanDuel Sportsbook).
Giants vs. Browns Injury Report & Latest News
Before you go to place your Giants vs. Browns picks, make sure to note the latest injury report following Thursday’s practice:
NY Giants:
- CB Nick McCloud (knee) - DNP
- LB Isaiah Simmons (not injury related) - DNP
- LB Darius Muasau (knee) - Limited
- LB Kayvon Thibodeaux (shoulder) - Limited
CLE Browns:
- DE Myles Garrett - Foot - DNP
- LS Charley Hughlett - Foot - Limited
- OT Dawand Jones - Knee - DNP to Limited
- TE David Njoku - Ankle - DNP
- DE Za’Darius Smith - Back - Limited
- RB Pierre Strong - Hamstring - DNP
- WR Jamari Thrash - Illness - Limited
- CB Denzel Ward - Shoulder - Limited
- OT Jedrick Wills - Knee - Limited
- DE Alex Wright - Triceps/Elbow - Limited
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Player News
Chiefs signed fourth-round WR Jalen Royals to a four-year contract.
Royals doesn’t have an obvious and open spot in the receiving corps to build short-term fantasy value with Xavier Worthy, Hollywood Brown, and Rashee Rice operating in the opening 11-personnel package. He may or may not play his way into WR4 duties depending on how the team feels about JuJu Smith-Schuster. Royals has plenty of talent and Brown is on a one-year deal, so there is a future where Royals is more than a bit player for the Chiefs. It likely won’t happen in his first season without injuries in front of him.
Matthew Judon said he “probably” won’t return to the Falcons in 2025.
The Falcons, of course, drafted both Jalon Walker and James Pearce in the first round. In an exclusive interview with CardPlayer.com — not to be confused with our PokerNews.com James Cook scoop a few days ago — Judon said that his sack total was down because “I dropped (into coverage) on 60 percent of the plays. It’s hard to get a pick and a sack on the same play.” Judon also told Kyle Odegard that “a couple” teams had expressed interest in him but he was in no rush to sign.
Jets released P Thomas Morstead.
Austin McNamara and Kai Kroeger will compete for the Jets punter job this year. The 39-year-old former Saint was the league’s oldest punter last season. If he wants to keep punting, he can absolutely join the tryout circuit or a competition elsewhere. But this is probably a sign that the Morstead’s 16-year career is close to an end at this point.
Lions offensive coordinator John Morton said it’s “going to be a breakout year” for Jameson Williams.
Morton said he’d never “been around someone that fast,” then quickly corrected himself to note that Jhamyr Gibbs is also that fast. Williams came on strong last year with a 58/1001/7 receiving line, but offensive coordinator praise could mean even more targets are coming. It would likely come at the expense of Amon-Ra St. Brown’s production if Williams were to truly break out, though there’s plenty for St. Brown to give and still be a top-flight fantasy wideout. It’s risky to read too much into statements like this in the offseason, but the new offensive coordinator telling you he thinks it’ll be a breakout year for Williams is certainly noteworthy.
Free agent CB Rasul Douglas is visiting the Seahawks on Tuesday.
It’s been a slow offseason for the veteran corner after a rough year with the Bills where he finished with just a 51.6 PFF coverage grade. The Dolphins have reportedly been in contact with Douglas, but this is the first known visit for him. He’d likely fit as a depth piece in Seattle, perhaps one that pushes Josh Jobe for a starting job outside in a best-case scenario.
Jets signed fourth-round WR Arian Smith to a four-year contract.
The good news for Smith is that he has a lot of depth chart runway. Garrett Wilson is the obvious No. 1, but neither Josh Reynolds nor Allen Lazard qualifies as a locked-in WR2 at this stage of their careers. Smith’s blazing speed has intrigued Aaron Glenn, who noted how fast he was in rookie minicamp over the weekend by simply noting “Arian has some juice.” The tough news is that as long as Justin Fields is the starter, it’s hard to believe he’ll be seeing many deep shots that aren’t schemed wide open. Still, Smith has some appeal in deeper leagues and could make an interesting dynasty stash.