Chargers vs. Chiefs Predictions, Picks & Odds: Week 14, Sunday Night Football 12/8

Jim Harbaugh and his Los Angeles Chargers already had one shot at the league-leading Kansas City Chiefs. And Kansas City was able to escape Los Angeles with a win. Now they’ll head to Arrowhead Stadium to play in one of the NFL’s toughest environments on the road.
Not only are the Chargers squarely in the playoff mix but the AFC West is still within reach. A win for the Chargers would drop the Chiefs to 11-2 with the Chargers at 9-4, right in shouting distance. We’ll run through all the stats, narratives, and injuries to see if they can pull it off in our Chargers vs. Chiefs NFL Week 14 predictions!
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Chargers vs. Chiefs Predictions For NFL Week 14, Sunday Night Football
Jim Harbaugh and Greg Roman have only been there for one loss. But Justin Herbert has been there for the last six straight. The Chargers are hoping to break a losing streak against the Chiefs that goes back to 2021.
The will be a tall task as the Chiefs have only last one game this year, a 30-21 loss to the Buffalo Bills on November 17th. The Chargers have been hot themselves, winning five of the last six. The loss came on Monday Night Football to Jim Harbaugh’s brother Jon and the Baltimore Ravens.
Los Angeles Chargers: Jim Harbaugh’s Physical Football
The Chargers have felt like a pass-happy organization going all the way back to the days of the Air Coryell offense. Dan Fouts, Philip Rivers, and Justin Herbert have all let it fly. But this new era with Jim Harbaugh and Greg Roman features a more physical, run-heavy attack. And it’s hard to argue with the results.
On defense the Chargers have been tremendous. They rank 6th in DVOA per FTN Fantasy and have been extra tough against the pass with stars like Asante Samuel Jr. and Derwin James. They did hold the Chiefs to 17 points, after all.
Kansas City Chiefs: Cruise Control
The Kansas City Chiefs have not really been blowing teams out like you would expect an 11-1 team to do. In fact they have the lowest margin of victory that an 11-1 team has ever had. But they are playing smart football and that translates to wins. Which is all that matters at the end of the day.
The Chiefs haven’t really needed to run up the score on their side in many games because their defense has been playing so well. They’ve been expecially tough against the run where they rank 8th in DVOA. They are currently allowing the third fewest rushing yards per game at only 87.8.
Chargers vs. Chiefs Odds, Spreads, Total & Betting Lines
As promised, the latest Chargers vs. Chiefs odds can be found below courtesy of BetMGM Sportsbook:
- Point Spread: Los Angeles Chargers -4 (-105) vs. Kansas City Chiefs +4 (-115)
- Money Line: Los Angeles Chargers (+165) vs. Kansas City Chiefs (-200)
- Game Total (Over/Under): Over 43 (-110) vs. Under 43 (-110)
Chargers vs. Chiefs: Game Total Under 43 (-110 at BetMGM Sportsbook)
This is just one of those games where the strengths and weakness of each team don’t quite matchup in a way that is conducive to scoring. It’s almost an unstoppable force meeting an immovable object in that sense.
The Chargers have been great against the pass. They have Derwin James who once famously “power bombed” Travis Kelce. And Asante Samuel can help limit DeAndre Hopkins. The Chiefs will likley need to go to the ground to make things happen on offense.
On the flip side, the Chargers jettisoned their top four pass-game weapons this off-season in Keenan Allen, Mike Williams, Austin Ekeler, and Gerald Everett. They still need to build out that part of the attack and, with their best pass-catcher Ladd McConkey banged up, Justin Herbert doesn’t have the tools he needs. The Chargers are missing starting running back JK Dobbins against one of the toughest run defenses so I’m going with under 43 points in this one. The last time they played there were 27 points scored.
Chargers vs. Chiefs Injury Report & Latest News
Finally, let’s take a quick look at the projected starting lineups for both teams heading into tonight’s matchup:
LAC Chargers
- LB Denzel Perryman- Doubtful
- WR Ladd McConkey - Questionable
- LB Junior Colston - Questionable
- S Tony Jefferson - Questionable
KC Chiefs
- WR Mecole Hardman - Questionable
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Player News
NBC Sports’ Matt Maiocco reports that the 49ers and OT D.J. Humphries do not have a deal in place.
Humphries reported on his social media account a few weeks ago that he had agreed to a contract with the 49ers, but that does not appear to be the case. At least for now. Humphries tore his ACL at the end of the 2023 season and was released by the Cardinals. He spent most of the 2024 season rehabbing before signing with the Chiefs. He started at left tackle in Week 14 before hurting his hamstring and missing the rest of the season. He will continue to search for another opportunity.
Patriots DT Christian Barmore (blood clots) will be ready to play in Week 1.
Barmore was limited to just four games last season while battling blood clots. He told reporters on Thursday that he’s been cleared for all football activity and has been a full participant in the Patriots’ offseason workout program. He expects to be fully ready by Week 1.
Raiders hired Brandon Hunt as Vice President of Player Personnel
Hunt was most recently the senior director of scouting for the Philadelphia Eagles and spent the previous two seasons as their director of scouting. Before joining the Eagles, Hunt spent 12 seasons (2010-21) as the pro scouting coordinator for the Pittsburgh Steelers.
ESPN’s Seth Wickersham reports Caleb Williams considered forcing a pre-draft trade from the Bears before ultimately deciding he could win in Chicago.
In other words, he mulled pulling an Elway. “Chicago is the place quarterbacks go to die,” were the words of Caleb’s father Carl to ESPN’s Seth Wickersham. Williams reportedly desired a trade to the Vikings, but he changed his mind after touring the Bears’ facility. “I can do it for this team,” Caleb reportedly told his dad. “I’m going to go to the Bears.” Williams acknowledged any attempt to force a trade would require going scorched earth on the Bears and city of Chicago, a process he did not have the stomach for. There have been zero reports of Bears/Williams drama since he made his peace with the idea, even after former coach Matt Eberflus’ clown show 2024 mistakes. It’s an interesting story, but one firmly planted in the past.
49ers signed No. 11 pick EDGE Mykel Williams to a four-year contract.
The deal is worth $24.9 million and is fully guaranteed. As is the case with all first-round picks, his contract includes a fifth-year option. The 49ers shed hundreds of millions of dollars in contracts this offseason and the bulk of those savings came on the defensive side of the ball. Defensive end was an obvious position of need and Williams was widely regarded as the best pass-rusher on the board when 49ers GM John Lynch was on the clock. Williams totaled five sacks in 2024 and left Georgia with 14 sacks across three seasons as a starter.
Vikings signed No. 24 pick OG Donovan Jackson to a four-year contract.
It’s a fully guaranteed deal worth $17.2 million with a fifth-year team option. Minnesota taking Jackson with the 24th-overall pick came as a bit of a surprise on draft night, but the Vikings needed offensive line help and Jackson was considered worthy of a first-round pick by some draftniks. He was primarily a left guard at Ohio State but successfully kicked out to tackle for the bulk of his senior season. Jackson is likely fated for guard duties in Minnesota, but the positional versatility remains a plus.