Underdog Fantasy MLB Picks May 22: Alec Bohm and Brandon Lowe in Good Matchups Tonight

Welcome to another week of daily fantasy baseball and MLB Underdog picks! We have some intriguing matchups on the MLB schedule for Monday night and plenty of ways to go for MLB daily picks and MLB player props. Our top MLB picks on Underdog Fantasy feature two hitters, Philadelphia Phillies 3B/1B Alec Bohm and Tampa Bay Rays 2B Brandon Lowe. Check out these free MLB player props and MLB daily picks on Underdog Fantasy for “Pick'Em” contests tonight. Don't forget to check out the latest MLB weather report and the confirmed MLB lineups when placing those MLB betting picks. Plus, the MLB daily projections and MLB Batter vs Pitcher page will help you find the best matchups for MLB player props and MLB DFS lineups. Now, let's dive into the top MLB player picks on Underdog Fantasy for Monday, May 22nd.
MLB Underdog Fantasy Top Picks May 22
Brandon Lowe, Tampa Bay Rays – OVER 1.5 Hits+Runs+RBI
On the surface, Brandon Lowe is having a subpar season with just a .204 batting average. He definitely hasn’t been as good as other Tampa Bay hitters like Yandy Diaz, Wander Franco, or Randy Arozarena. Still, the lefty-hitting second baseman can be a key run-producer for the Rays in the right situations. That’s what we’re targeting tonight with Toronto Blue Jays right-hander Chris Bassitt on the mound. First off, Bassitt is due for some negative regression with a 4.52 FIP that’s way higher than his 3.05 ERA, not to mention a .197 BABIP as well. Lowe should be hitting third or fourth in the Tampa lineup and have plenty of RBI opportunities. As for Lowe’s own hitting, he’s on a mini hot streak lately with a .320 BA over the past seven games. For what it’s worth, Lowe is 1-for-3 in his career vs. Bassitt with that one hit being a homer.
Alec Bohm, Philadelphia Phillies – OVER 0.5 Singles
Betting on a singles prop is always risky, but it makes sense for a guy like Alec Bohm. The Philadelphia Phillies’ corner infielder actually had the fifth-most singles in the whole MLB last season with 131. He has the power to knock home runs and extra-base hits, but Bohm’s technique at the plate is to take what pitchers give him, which includes plenty of singles. Of his 45 hits so far this year, 32 have been single-baggers. Look for Bohm to have success at the plate tonight against Arizona Diamondbacks left-hander Tommy Henry. The young starter has a 5.00 ERA and 1.48 WHIP this season and he’s particularly struggled on the road. Bohm, meanwhile, hit .352 against lefties last year and is batting .275 against southpaws this season.
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Player News
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.
José Soriano allowed three runs over five innings while not factoring in the decision Thursday against the Blue Jays.
Soriano left with a 4-3 lead, but it was erased quickly after his departure. The 26-year-old was not exactly dominant in his outing with eight hits allowed and four free passes, but he did strike out six to help balance things out a smidgen. Soriano takes an even ERA of 4.00 into a scheduled start against the Padres in San Diego on Tuesday. There should be better options for that one.