PrizePicks MLB Picks On Wednesday, 7/24: Expert DFS Plays & Projections

We have baseball kicking off nice and early today as the first game of the day starts at 12:20 pm ET and that presents us with plenty of options for today’s MLB PrizePicks plays of the day.
Two of our early favorites are Luis Castillo of the Seattle Mariners and Willson Contreras of the St. Louis Cardinals. With how much baseball there is today, there are numerous opportunities to discover the perfect selections!
PrizePicks MLB Picks Today: Wednesday, 7/24
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Luis Castillo PrizePicks MLB Pick: More Than 34.5 Pitcher Fantasy Score
This is a fantastic matchup for Luis Castillo and the Seattle Mariners as they face off against the Los Angeles Angels. During the month of July, the Angels have a team OPS of .612, wOBA of .278, which both rank 28th in the league, while flashing zero power and ranking 30th in ISO.
After a rough month of June, Luis Castillo has started off July better than any other month this year pitching to a 1.83 ERA and .176 BAA. Castillo has a 3.07 ERA at home compared to 4.11 on the road, a 25.7% K-rate compared to 20.9% on the road. Castillo is a big favorite, poised for a quality start, and poised to go well soar north of this fantasy score.
Willson Contreras PrizePicks MLB Pick: More Than 7.0 Fantasy Score
Left-handed masher, that’s what Willson Contreras’ nickname should be. Yeah, bad joke, sure, but he’s been so good against southpaws this year. Against them, he’s posted a .978 OPS, .256 ISO, and a .418 wOBA.
Contreras and the Cards face off against Martin Perez who’s been awful against everyone this year, righties included. Right-handed bats have posted a .318 AVG, .531 SLG%, and .394 wOBA against Perez.
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Player News
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.
José Soriano allowed three runs over five innings while not factoring in the decision Thursday against the Blue Jays.
Soriano left with a 4-3 lead, but it was erased quickly after his departure. The 26-year-old was not exactly dominant in his outing with eight hits allowed and four free passes, but he did strike out six to help balance things out a smidgen. Soriano takes an even ERA of 4.00 into a scheduled start against the Padres in San Diego on Tuesday. There should be better options for that one.