PrizePicks MLB Picks For Today, 4/29: Expert DFS Plays & Projections

We are back for another day of PrizePicks MLB Pick'em! As we delve into the matchups for April 29th, let's explore two compelling picks that could make all the difference in your PrizePicks lineup.
PrizePicks MLB Picks Today: Monday, April 29
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Now, let's get into the picks!
James Paxton, Los Angeles Dodgers
James Paxton, the formidable pitcher for the Los Angeles Dodgers, has undoubtedly showcased moments of brilliance throughout his career. However, the early stages of this season have seen him struggle to find his rhythm, particularly in terms of control. With at least three walks in three of his four starts, including alarming outings of five and eight walks, Paxton's command issues have been a cause for concern.
Adding to his challenges is the formidable lineup of the Arizona Diamondbacks, a team known for their proficiency against left-handed pitching. Paxton's propensity for giving up walks coupled with the Diamondbacks' prowess at the plate against southpaws could spell trouble for the Dodgers' hurler. Therefore, opting for Paxton to score less than 18.5 fantasy points seems like a prudent choice in this matchup.
- Pick: Less Than 18.5 Fantasy Score
Luis Rengifo, Los Angeles Angels
Shifting our focus to the offensive side of the game, we turn our attention to Luis Rengifo of the Los Angeles Angels. Rengifo has proven himself to be a force to be reckoned with, particularly when facing left-handed pitchers. Over the last three seasons, he has exhibited elite numbers against southpaws, boasting an impressive average ISO exceeding .200, a slugging percentage surpassing .550, and wOBA figures exceeding .380.
With such formidable statistics in his favor, Rengifo presents a compelling case for exceeding 1.5 Hits+Runs+RBIs in this matchup. His ability to consistently deliver impactful performances against left-handed pitching positions him as a key player to watch on the field. As the Angels take on their opponents, Rengifo's potential to make a significant contribution to his team's offensive output cannot be underestimated.
- Pick: More than 1.5 Hits+Runs+RBI
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Player News
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.
José Soriano allowed three runs over five innings while not factoring in the decision Thursday against the Blue Jays.
Soriano left with a 4-3 lead, but it was erased quickly after his departure. The 26-year-old was not exactly dominant in his outing with eight hits allowed and four free passes, but he did strike out six to help balance things out a smidgen. Soriano takes an even ERA of 4.00 into a scheduled start against the Padres in San Diego on Tuesday. There should be better options for that one.