Matt McLain PrizePicks MLB Picks Today, 3/27: Free DFS Picks & Projections

It’s MLB Opening Day and that means we’re gearing up to play on PrizePicks and start winning some money with our PrizePicks MLB picks today.
You don’t have to be a hapless romantic to know how magical the first day of the baseball season can be. From moments like the Opening Day lineups being announced to watching the Los Angeles Dodgers receive their championship rings to the final out of a team’s first win of the season, this day is unlike any other.
There is an air of hope and promise for each and every team and it marks a clean slate for all of us to get back into the DFS pick ‘em world and start building that bankroll once again. With 14 games from which to choose, this is going to be a fun day of picks and predictions.
PrizePicks Fantasy Picks for 2025 MLB Opening Day: MLB DFS Projections
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Matt McLain MLB PrizePicks Fantasy Pick: More Than 0.5 Hits
Tough to invest in a player who missed all of last season with an injury? For sure. But McLain is one of my favorites having watched him work his way up the minor league ranks and slashing .290/.357/.507 during his rookie campaign.
He’s always been a strong on-base guy and we’re taking him for a hit against Logan Webb instead of his total bases because his walk rate in the majors is a little low. He got off to a hot start this spring but has been a little quiet over his last few spring games. It’s the calm before the storm. Get in on it now!
- Pick: More Than 0.5 Hits
Nathan Eovaldi MLB PrizePicks Fantasy Pick: Less Than 5.5 Strikeouts
Not only do we have Rangers manager Bruce Bochy likely holding Eovaldi back from throwing too many pitches here on Opening Day, but the veteran righthander has struggled through 13 spring innings, posting a 5.54 ERA, but, more importantly, just a 6.23 K/9 which is the lowest he’s posted since the 2012 season.
The Red Sox lineup is expected to be quite formidable, and they should have little trouble getting to their former teammate and sending him to the showers a little early.
- Pick: Less Than 5.5 Strikeouts
Rhys Hoskins MLB PrizePicks Fantasy Pick: More Than 1.5 Hits + Runs + RBI
You can go brazen and pick him to hit a home run and I wouldn’t be upset with making that call, but we’re going to ease into the season and maybe play it a little less bold. The HRR pick is still a “demon,” so we’re getting a better payout than if we were to look at his total bases, but I don’t feel the need to go any further on that.
A home run will clear this pick for us, but so will an RBI-single, so let’s keep it simple. I don’t have much faith in Carlos Rodon to keep this Brewers lineup at bay and with the way Hoskins has looked at the plate this spring, I’m ready to invest.
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Player News
Tobias Myers (oblique) could begin a rehab assignment next week.
Brandon Woodruff (shoulder) is throwing a simulated game on Tuesday as he nears a rehab assignment.
Matt Wallner and Trevor Larnach are not in the lineup for the Twins on Monday against the White Sox.
Sean Bouchard will start in right field for the Rockies on Monday against the Phillies.
Jonathan India is starting at third base and batting leadoff for the Royals on Monday against the Brewers.
Triston Casas is not in the lineup for the Red Sox on Monday.