Matt McLain PrizePicks MLB Picks Today, 3/27: Free DFS Picks & Projections

It’s MLB Opening Day and that means we’re gearing up to play on PrizePicks and start winning some money with our PrizePicks MLB picks today.
You don’t have to be a hapless romantic to know how magical the first day of the baseball season can be. From moments like the Opening Day lineups being announced to watching the Los Angeles Dodgers receive their championship rings to the final out of a team’s first win of the season, this day is unlike any other.
There is an air of hope and promise for each and every team and it marks a clean slate for all of us to get back into the DFS pick ‘em world and start building that bankroll once again. With 14 games from which to choose, this is going to be a fun day of picks and predictions.
PrizePicks Fantasy Picks for 2025 MLB Opening Day: MLB DFS Projections
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Matt McLain MLB PrizePicks Fantasy Pick: More Than 0.5 Hits
Tough to invest in a player who missed all of last season with an injury? For sure. But McLain is one of my favorites having watched him work his way up the minor league ranks and slashing .290/.357/.507 during his rookie campaign.
He’s always been a strong on-base guy and we’re taking him for a hit against Logan Webb instead of his total bases because his walk rate in the majors is a little low. He got off to a hot start this spring but has been a little quiet over his last few spring games. It’s the calm before the storm. Get in on it now!
- Pick: More Than 0.5 Hits
Nathan Eovaldi MLB PrizePicks Fantasy Pick: Less Than 5.5 Strikeouts
Not only do we have Rangers manager Bruce Bochy likely holding Eovaldi back from throwing too many pitches here on Opening Day, but the veteran righthander has struggled through 13 spring innings, posting a 5.54 ERA, but, more importantly, just a 6.23 K/9 which is the lowest he’s posted since the 2012 season.
The Red Sox lineup is expected to be quite formidable, and they should have little trouble getting to their former teammate and sending him to the showers a little early.
- Pick: Less Than 5.5 Strikeouts
Rhys Hoskins MLB PrizePicks Fantasy Pick: More Than 1.5 Hits + Runs + RBI
You can go brazen and pick him to hit a home run and I wouldn’t be upset with making that call, but we’re going to ease into the season and maybe play it a little less bold. The HRR pick is still a “demon,” so we’re getting a better payout than if we were to look at his total bases, but I don’t feel the need to go any further on that.
A home run will clear this pick for us, but so will an RBI-single, so let’s keep it simple. I don’t have much faith in Carlos Rodon to keep this Brewers lineup at bay and with the way Hoskins has looked at the plate this spring, I’m ready to invest.
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Player News
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.
José Soriano allowed three runs over five innings while not factoring in the decision Thursday against the Blue Jays.
Soriano left with a 4-3 lead, but it was erased quickly after his departure. The 26-year-old was not exactly dominant in his outing with eight hits allowed and four free passes, but he did strike out six to help balance things out a smidgen. Soriano takes an even ERA of 4.00 into a scheduled start against the Padres in San Diego on Tuesday. There should be better options for that one.