March Madness has arrived, and the excitement grows as the tournament progresses. This year, the NCAA Men's Basketball Tournament offers fans an exciting lineup of first-round games that could significantly alter the championship series. 

As we enter the second day of the Round of 64, both dedicated basketball enthusiasts and sports bettors are eager to engage in thrilling matchups. With the potential for buzzer-beaters and the intense atmosphere of crucial games, today's events are set to create memorable experiences. 

In this article, we will share the full schedule for Day 2 of March Madness, expert March Madness Round of 64 picks with insights on key matchups, information on how to watch the games live, and the latest odds to assist you in making smart betting choices.

 

 

 

March Madness Round Of 64 Day 2 Schedule For Today, 3/21

Here’s the complete lineup of the March Madness Round of 64 games taking place today: 

  • (8) Mississippi State vs. (9) Baylor, 12:15 p.m. | CBS
  • (2) Alabama vs. (15) Robert Morris, 12:40 p.m. | truTV
  • (3) Iowa State vs. (14) Lipscomb, 1:30 p.m. | TNT
  • (5) Memphis vs. (12) Colorado State, 2:00 p.m. | TBS
  • (1) Duke vs. (16) Mount St. Mary's, 2:50 p.m. | CBS
  • (7) Saint Mary's vs. (10) Vanderbilt, 3:15 p.m. | truTV
  • (6) Ole Miss vs. (11) North Carolina, 4:05 p.m. | TNT
  • (4) Maryland vs. (13) Grand Canyon, 4:35 p.m. | TBS
  • (1) Florida vs. (16) Norfolk State, 6:50 p.m. | TNT
  • (3) Kentucky vs. (14) Troy, 7:10 p.m. | CBS
  • (7) Marquette vs. (10) New Mexico, 7:25 p.m. | TBS
  • (4) Arizona vs. (13) Akron, 7:35 p.m. | truTV
  • (8) UConn vs. (9) Oklahoma, 9:25 p.m. | TNT
  • (6) Illinois vs. (11) Xavier, 9:45 p.m. | CBS
  • (2) Michigan State vs. (15) Bryant, 10:00 p.m. | TBS
  • (5) Oregon vs. (12) Liberty, 10:10 p.m. | truTV

 

 

 

March Madness Round Of 64 Day 2 Expert Picks & Best Bets

As the games kick off today, here are the expert March Madness Round of 64 picks for two enticing matchups:

Marquette vs. New Mexico Prediction Today, 3/21: March Madness Round Of 64

  • Why Marquette Can Win

Marquette comes into this matchup as a solid favorite. The Golden Eagles have showcased their potential throughout the season, primarily due to their dynamic offense and a defense that generally stays strong under pressure. Marquette averages 76.9 points per game, ranking them as one of the more prolific scoring teams in the tournament. Guard Kam Jones leads the charge, putting up 19.3 points per game this season while shooting nearly 49% from the field.

  • New Mexico’s Challenge

New Mexico boasts a strong offensive lineup, averaging 81.2 points per game, which ranks 28th nationally. However, their defense allows 70.8 points, putting them at a disadvantage against Marquette’s offensive firepower. With a three-point shooting percentage of just 34.7%, New Mexico must be exceptionally efficient to keep up. 

Considering Marquette's ability to pressure opponents and convert on critical possessions, betting on Marquette -3.5 seems to be a solid pick for this matchup.

 

 

 

UConn vs. Oklahoma Prediction Today, 3/21: March Madness Round Of 64

  • Why Oklahoma Can Cover

Oklahoma enters the tournament with a potent offensive attack, averaging 78.9 points per game. With an impressive shooting percentage of 47.2% from the field, Oklahoma has the capacity to score against a UConn defense that, although effective, has shown vulnerabilities throughout the season. The Sooners have several players, including Jeremiah Fears, who can take over a game, making them dangerous against higher seeds.

  • UConn's Strengths & Weaknesses

UConn has an average of 77.4 points per game, and their defense is substantially better than Oklahoma's. However, they can falter against teams that stretch their limits.

With this being a tight matchup early in the tournament, the spread of +5.5 in favor of Oklahoma might provide an excellent value bet for those looking at the underdog option.

 

 

 

How To Watch 2025 March Madness First Round Games

Fans can enjoy all the excitement of March Madness Day 2 through several ways to watch:

  • CBS: You can find some games on your local CBS stations. If you prefer streaming, check out Paramount+.
  • TNT, TBS, truTV: These channels are easily accessible with cable subscriptions and also on streaming services like YouTube TV, Hulu + Live TV, and Sling TV.
  • March Madness Live: The NCAA's official streaming service offers live streaming for every game.

 

 

 

2025 March Madness Round Of 64 Odds & Betting Lines Via BetMGM Sportsbook

Check out the betting odds for today's March Madness Round of 64 games, provided by BetMGM Sportsbook: 

  • Mississippi State (-1.5) vs. Baylor – O/U 145.5
  • Alabama (-21.5) vs. Robert Morris – O/U 166.5
  • Iowa State (-14.5) vs. Lipscomb – O/U 143.5
  • Colorado State (-1.5) vs. Memphis – O/U 147.5
  • Duke (-32.5) vs. Mount St. Mary's – O/U 140.5
  • Saint Mary's (-4.5) vs. Vanderbilt – O/U 135.5
  • North Carolina (-1.5) vs. Ole Miss – O/U 155.5
  • Maryland (-10.5) vs. Grand Canyon – O/U 149.5
  • Florida (-28.5) vs. Norfolk State – O/U 153.5
  • Kentucky (-11.5) vs. Troy – O/U 151.5
  • Marquette (-3.5) vs. New Mexico – O/U 152.5
  • Arizona (-14.5) vs. Akron – O/U 167.5
  • UConn (-5.5) vs. Oklahoma – O/U 148.5
  • Illinois (-3.0) vs. Xavier – O/U 160.5
  • Michigan State (-17.5) vs. Bryant – O/U 152.5
  • Oregon (-7.5) vs. Liberty – O/U 139.5

The second day of the March Madness Round of 64 promises to be full of excitement. Make sure to watch these matchups, and may the best teams move forward as you enjoy the thrill of the games and your March Madness Round of 64 picks!