PrizePicks NFL DFS For Saturday, 12/28: Expert Picks, Projections & More

As Week 17 of the 2024 NFL season unfolds, two standout players to target on PrizePicks are Los Angeles Rams RB Kyren Williams and Los Angeles Chargers WR Ladd McConkey. Both have favorable matchups and enticing projections that align with recent trends.
PrizePicks NFL DFS Picks for Saturday NFL Week 17 12/28
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Kyren Williams PrizePicks Pick: Over 92.5 Rushing Yards
Kyren Williams continues to be a workhorse for the Rams, ranking among the NFL’s leading rushers with 1,243 yards through 16 weeks. He has hit the 100-yard mark in three of his last four games, including back-to-back performances.
Volume is a significant factor in Williams’ success, with 29 rushing attempts in two of his last three outings. The Rams enter this game as home favorites against the Cardinals, and if they take an early lead, Williams will likely see a heavy workload to close out the game. His projection of 92.5 rushing yards aligns perfectly with his current form.
- PrizePicks Pick: Over 92.5 Rushing Yards
Ladd McConkey PrizePicks Pick: Over 74.5 Receiving Yards
Ladd McConkey has been a revelation for the Chargers in his rookie campaign. While many speculated the Patriots would draft him, they chose Jay'Lyn Polk instead—a decision that hasn’t paid off. Meanwhile, McConkey has excelled, solidifying himself as a key target and helping the Chargers transition from the Keenan Allen era.
McConkey's projection of 74.5 receiving yards is reasonable given his role in the offense. He typically lines up in the slot, avoiding New England’s standout cornerback Christian Gonzalez, who primarily defends the outside. McConkey has surpassed 74.5 receiving yards in four of his last five games, and with the Chargers’ passing attack finding its rhythm, he’s in a prime position to deliver again.
- PrizePicks Pick: Over 74.5 Receiving Yards
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Player News
Dak Prescott said George Pickens is “more than a 50-50 catcher.”
Prescott in a Wednesday morning radio interview was effusive in his praise of Pickens, who was traded last week from the Steelers to Dallas in exchange for draft compensation. “You put the ball anywhere in his vicinity, very strong hands,” Prescott said of Pickens. “He’s more than a 50-50 catcher. ... I’m excited for him. I know that we need some help at that position.” Pickens, 24, who has 2,841 receiving yards and 12 touchdowns over three NFL seasons, is widely expected to see more single coverage in Dallas than he did as the unquestioned No. 1 wideout in Pittsburgh. Opposing coverage units won’t be able to shade safeties toward his side of the field with CeeDee Lamb threatening the middle of the field. Pickens shapes up as a volatile WR2/3 in 2025.
The Lions will play the Vikings on Christmas Day.
The Week 17 matchup between longtime NFC North rivals will be available exclusively on Netflix. Coming off a devastating Divisional Round loss to Washington last January, the Lions will be prominently featured by the league in 2025. Jared Goff and the Lions beat Minnesota twice during the 2024 regular season: A 31-29 Week 7 victory in Minnesota and a 31-9 Week 18 drubbing in Detroit. Goff combined to throw for 511 yards, three touchdowns, and no interceptions in those games. Justin Jefferson, meanwhile, was limited to ten catches for 131 yards and a touchdown in the Vikings’ 2024 games against Detroit.
The Eagles will face the Chiefs in Week 2.
The NFL’s trickle of 2025 schedule news includes a Super Bowl rematch in Kansas City, where Patrick Mahomes and company will look for a little revenge after getting bulldozed by the Eagles in Super Bowl LIX, 40-22. Philadelphia’s elite defense held Mahomes to a mere 226 yards on 32 pass attempts, with much of that production coming in fourth quarter garbage time. Jalen Hurts threw of two scores and ran in another as Saquon Barkley was held in check to the tune of 57 scoreless yards on 23 carries. If the Chiefs are to get back at the Eagles in Week 2, they’ll have to do a far better job of protecting Mahomes.
The Athletic’s Mike DeFabo believes RB Kaleb Johnson is a “schematic fit” for the Steelers offense.
Johnson, a third-round draft pick who last month was listed as a co-starter alongside Jaylen Warren on the Pittsburgh depth chart, was a hyper-productive back in Iowa’s zone-based rushing scheme, a system used frequently in Arthur Smith’s run-first offense. Only three college running backs in 2024 logged more zone rushes than Johnson. Johnson’s goals in offseason practices, according to DeFabo, “are to learn the playbook and earn the coaching staff’s trust with the hope of becoming an ‘every-down back’ sooner rather than later.” That might require Johnson to improve his pass blocking. The rookie said he’s worked on that with Warren — one of the best blocking backs in the NFL — in recent days.
The Chiefs will play the Cowboys on Thanksgiving Day.
The Week 13 matchup will bring Patrick Mahomes and the AFC champion Chiefs to Dallas for the day’s late afternoon game. It could be a shootout if key players on both sides are healthy. Dak Prescott heads into the season with George Pickens as a legit WR2 behind CeeDee Lamb, and Mahomes — who has talked this offseason about more explosive plays for the KC offense — will have Xavier Worthy, Travis Kelce, Rashee Rice, and Hollywood Brown at his disposal. Mahomes has faced Dallas once in his NFL career, a Week 11 win in 2021 in which he threw for 260 scoreless yards. The hope for both the league and fantasy managers is that the Cowboys are still in postseason contention by the end of November.
Free agent Gabe Davis will visit the New York Giants.
Cut by the Jaguars after one season last week, Davis visited the 49ers on Monday. New York would be a reunion of sorts, as he played for Giants coach Brian Daboll in Buffalo. The G-Men already have several wideouts capable of stretching the field, but 26-year-old Davis could still be a decent role player in a strong offense. The problem, of course, is that the Giants profile as anything but, but rookie QB Jaxson Dart is comfortable throwing down the field.