Buccaneers vs. Saints Predictions, Picks & Odds: NFL Week 6, Sunday 10/13

Two of the most impressive teams to begin the 2024-25 NFL season, especially in comparison to expectations, were the Tampa Bay Buccaneers and New Orleans Saints. However, these NFC South rivals are now chasing the Atlanta Falcons in the division, and for their Week 6 matchup, we’ve shared our best Buccaneers vs. Saints predictions.
To go along with the best bet from our Buccaneers vs. Saints picks will also be a brand new $300 FanDuel Sportsbook promotion, so we’ve got you set up for a great weekend overall!
Buccaneers vs. Saints Predictions For NFL Week 6, Sunday 10/13
After a 3-0 start to the season for the Bucs and an absolutely dominant 2-0 Saints, it looked as though the NFC South would finally be a strong division and set the pace for the entire league. Let’s not forget, it was just two seasons ago that they won the division with a losing record!
Well, Tampa has now lost two of their last three games, while the Saints have now dropped three straight. In that span for both teams, they also lost games to the division rival Atlanta Falcons. All that to say that it’s difficult to trust either side in this matchup.
However, given the Buccaneers vs. Saints odds, we feel as though there is incredible value to be had.
Tampa Bay Buccaneers: Taking The Rest Advantage
Before we fully dive into the best bet from our Buccaneers vs. Saints predictions, how can Tampa take this game? They’re actually favored on the road, and given the recent hurricane hitting virtually Tampa directly, it’s a good thing.
Ironically enough, New Orleans knows all about the aftermath of hurricanes, but regardless - the Bucs’ chances. They were taken to overtime by the Falcons in their most recent matchup, but that was way back on Thursday Night Football of Week 5, so they’ll have had 10 days off.
That doesn’t mean it will be an easy game to take by any means, but given the injuries they’ve needed to recover from, it could certainly make the difference.
New Orleans Saints: Stopping The Skid
As mentioned, the Saints’ skid is a real one. After dominating their first two games by final scores of 47-10 and 44-19, they’ve since dropped three straight games. However, it’s worth noting that the first of those two losses came by three and two points, while the most recent came by the hands of the back-to-back defending champs - the Kansas City Chiefs.
So, is it panic time in the Bayou? There are certainly fans on both sides of the coin, especially with the question marks surrounding QB Derek Carr. He’s been injury prone the past few seasons, and that is now the case yet again. Of course, we’re all familiar with the Swiss Army knife that is Taysom Hill that will almost certainly take some snaps.
Buccaneers vs. Saints Odds, Spreads, Total & Betting Lines
We stated that we found some great value in the latest Buccaneers vs. Saints odds, which you can see below provide by FanDuel Sportsbook:
- Point Spread: Tampa Bay Buccaneers -3.5 (-115) vs. New Orleans Saints +3.5 (-105)
- Money Line: Tampa Bay Buccaneers (-186) vs. New Orleans Saints (+156)
- Game Total (Over/Under): Over 41.5 (-110) vs. Under 41.5 (-110)
Buccaneers vs. Saints Predictions: New Orleans +3.5 (-105 at FanDuel Sportsbook)
First and foremost, we know that the elephant in the room when it comes to us backing New Orleans with our Buccaneers vs. Saints predictions is the status of Carr. At this point in the week, we’re going to proceed as if he won’t be on the field.
If he is somehow able to suit up, then we’ll only be more pleased with having 3.5 points in our pocket with a Saints team at home. After all, the Caesars Superdome is among the most difficult places to play for the opposition, so we’re quite surprised to see New Orleans listed as such clear underdogs.
While Carr is the most significant reason for that, the Saints are one team that have proven that they can get the job done in a variety of ways. That’s thanks to Hill, and whether you love him or find him annoying (certain fantasy football platforms make it that way), the fact of the matter is that he’s capable of anything.
Let’s also not gloss over the fact that Saints RB Alvin Kamara has still be better than expected based on what many said about his age, and WR Chris Olave can definitely exploit a Tampa secondary allowing the fifth-most passing yards per game.
With all that in mind, we’re taking New Orleans +3.5 (-105 at FanDuel Sportsbook) with the best bet from our Buccaneers vs. Saints predictions.
Buccaneers vs. Saints Injury Report & Latest News
Carr headlines the injury news across this matchup, and you can see the latest updates after Thursday’s practice:
TB Buccaneers:
- S Antoine Winfield - LP
- S Jordan Whitehead - LP
- WR Jalen McMillan - LP
- RB Rachaad White - DNP
- WR Trey Palmer - DNP
- DB Christian Izien - DNP
- C Graham Barton - DNP
- DL William Gholston - DNP
- WR Kameron Johnson - DNP
NO Saints:
- WR Rashid Shaheed - LP
- RB Alvin Kamara - LP
- LB Pete Werner - DNP
- S Will Harris - DNP
- C/G Lucas Patrick - DNP
- QB Derek Carr - DNP
- DE Payton Turner - DNP
- G Cesar Ruiz - DNP
- TE Taysom Hill - DNP
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Player News
Packers signed WR Bo Melton, RB Emanuel Wilson, and P Daniel Whelan to their exclusive rights free agent tenders.
Melton caught on with the Packers in 2023, totaling 16 receptions for 218 yards and a touchdown in five games. He added eight receptions for 91 yards in 17 games last season. Melton will continue to be a depth piece in an already-deep Packers wide receiver room. Wilson has also been with the Packers for two seasons and rushed for 502 yards and four touchdowns as Josh Jacobs’ immediate backup last season. He will compete with MarShawn Lloyd for that role again. Whelan is the team’s punter and will be back for 2025. All three signed their exclusive rights free agent tender and will essentially be on one-year contracts this season.
Seahawks re-signed Johnathan Hankins to a one-year contract.
Hankins hasn’t had a PFF run defense grade above 52.4 since 2020 and is primarily called on to play early downs. He turned 33 in March. He’ll be a complimentary piece behind Jarran Reed and Byron Murphy II if he makes the roster out of training camp.
Chargers placed the UFA tender on RB J.K. Dobbins.
This gives the Chargers exclusive negotiating rights if he does not sign with a team by July 22 or the first 2025 NFL training camp opens, whichever comes first. The tag is mainly useful for compensatory pick reasons as Dobbins will still count towards Los Angeles’ haul in the formula if signed before then. The Chargers currently do not project to add a pick in 2026 per Over The Cap’s Nick Korte.
49ers signed OT D.J. Humphries.
Humphries played in only two games for the Chiefs last year as he spent most of the season rehabbing a late 2023 torn ACL on his own. He wasn’t appreciably good in either of those games, but he was rusty and does have a history of better than that. Entering his age-32 season for the 49ers, he’ll probably be trying to win the right tackle job opposite Trent Williams in training camp.
Patriots released LS Joe Cardona.
The team selected his replacement, Julian Ashby, in the seventh round of the draft. This snapper of balls who are longer than usual is only 33, and it’s possible he picks up his career elsewhere. There aren’t too many remaining Patriots Regimes in the wild in 2025, but Nick Caserio does still run the Texans and they let Jon Weeks walk this offseason so that’s one speculative fit.
NewOrleans.Football’s Nick Underhill said he would be “flabbergasted” if Derek Carr played for the Saints this year.
“I would have trouble understanding why you would allow that to happen, you’re trying to build a new culture, you can’t let that guy ... you just got a rookie QB, this is the example you’re going to give him,” Underhill continued. Both Underhill and Mike Triplett believe Tyler Shough will be starting for the Saints in Week 1, with Underhill saying he had “80 percent or higher odds to start 80 percent of the games this year.” Shough would be an uninspiring superflex pick, perhaps a QB3, but given how things have played out with Carr over the past months it sure doesn’t seem like the Saints have a reason to want to continue this relationship. Mickey Loomis literally asked reporters to stop asking him Carr questions at his pre-draft press conference.