NFL Injury Report 2024 - Fantasy Football Week 3: Christian McCaffrey & More

We’re not even fully through two weeks of the NFL season and the amount of fantasy football injuries is longer than a target shopping list.
NFL Injury Report For Week 3: Fantasy Football Injuries
In this article, we’re diving into all of the injuries that took place this past week so we know where we should focus our attention for the Week 3 waiver wire and who will likely be replaced, placed on injured reserve or who’s going to be a game-time decision.
We’ll know more when the Wednesday injury reports drop around the league, but without further ado, here is the NFL Injury Report for Week 3!
NFL Week 3 Injury Report: Quarterbacks
Justin Herbert Injury Update - Leg
Despite returning to the Chargers Week 2 game, they sent their star quarterback to get an MRI on his leg and thankfully, head coach Jim Harbaugh said things came back negative. We’ll know what his practice status will be come Wednesday.
Jordan Love Injury Update - Knee
There have been a LOT of conflicting reports about Jordan Love and when he’ll return to the field, but here is ESPN’s Rob Demovsky discussing Love’s Week 3 status on ESPN radio. His reporting suggests Love is very live to play in Week 3. His injury status is one of the more relevant fantasy football injuries there is.
NFL Week 3 Injury Report: Running Backs
Christian McCaffrey Injury Update - Calf/Achilles
Over the weekend, the 49ers officially placed Christian McCaffrey on injured reserve keeping him out for at least the next four weeks. The reports suggest it might be longer than four weeks, however. NFL’s Ian Rapoport reported it could be six weeks or so.
Isiah Pacheco Injury Update - Fibula
It’s been confirmed that Isiah Pacheco has a fractured fibula and will miss an extended period of time. He’s been placed on injured reserve and is expected to miss six to eight weeks per Jeremy Fowler.
Joe Mixon Injury Update - Ankle
Mixon, who was victim of the hip-drop tackle in Week 2, was one of many fantasy football injuries at the running back position. He went for an MRI on his ankle on Monday and we’ll see what happens from there. The Texans play the Vikings in Week 3.
Rachaad White Injury Update - Groin
Per Jeremy Fowler of ESPN, Rachaad White’s groin injury isn’t much of a concern at this time. We’ll see if anything changes on that front when the Bucs first practice report comes out on Wednesday.
Tyjae Spears Injury Update - Ankle
Head coach Brian Callahan noted at his post-game presser on Sunday that Spears had left late in the game with a minor ankle sprain and that’s been confirmed on Monday. He considers Spears “day to day” and we’ll see about Wednesday’s practice when the team’s first report comes out.
Tank Bigsby Injury Update - Shoulder
We’ll see how the week progresses and what Bigsby is able to do at practice when the first report takes place on Wednesday, but head coach Doug Pederson said he’s good to go moving forward.
NFL Week 3 Injury Report: Wide Receivers
Cooper Kupp Injury Update - Ankle
After leaving the Rams Week 2 blowout loss, it was reported by Jourdan Rodrigue of the Athletic, that Cooper Kupp left the locker room in a walking boot. It is now being reported by Adam Schefter that Kupp is expected to miss an extended period of time and is a candidate for injured reserve, per head coach Sean McVay.
Justin Jefferson Injury Update - Quad
After the game, reporters asked Justin Jefferson about his quad injury and he said he’s not overly concerned and that it’s nothing more than a thigh bruise/contusion. The Vikings are listing Jefferson as day to day.
Amon-Ra St. Brown Injury Update - Leg
Head coach Dan Campbell has stated that Amon-Ra St. Brown’s injury is a soft-tissue issue and it’s nothing to be concerned about long term. Campbell said St. Brown is day to day.
A.J. Brown Injury Update - Hamstring
After feeling his hamstring tighten up during Friday’s practice, he sat out on Saturday and was ultimately ruled out for Monday Night Football on Sunday. Philadelphia has a short week heading into Week 3, so it’s possible this could turn into a multi-week injury for the Eagles number one receiver.
Gabe Davis Injury Update - Shoulder
Head coach Doug Pederson noted on Monday that despite hurting his shoulder on Sunday, this is not one of the fantasy football injuries we should worry about. Pederson said Davis will be OK.
NFL Week 3 Injury Report: Tight Ends
Evan Engram Injury Update - Hamstring
After injuring his hamstring during pregame warmups of the Jaguars Week 2 contest, head coach Doug Pederson has listed Evan Engram as week to week.
Taysom Hill Injury Update - Chest
Hill went to the hospital after the Saints Week 2 win because of a chest injury but everything came back OK, and it’s believed that this is nothing serious.
Jake Ferguson Injury Update - Knee
Stephen Jones, Cowboys EVP, went on 1053thefan and said Ferguson was very close to playing in Week 2 and the team expects him to suit up in Week 3.
Player News
49ers signed No. 11 pick EDGE Mykel Williams to a four-year contract.
The deal is worth $24.9 million and is fully guaranteed. As is the case with all first-round picks, his contract includes a fifth-year option. The 49ers shed hundreds of millions of dollars in contracts this offseason and the bulk of those savings came on the defensive side of the ball. Defensive end was an obvious position of need and Williams was widely regarded as the best pass-rusher on the board when 49ers GM John Lynch was on the clock. Williams totaled five sacks in 2024 and left Georgia with 14 sacks across three seasons as a starter.
Vikings signed No. 24 pick OG Donovan Jackson to a four-year contract.
It’s a fully guaranteed deal worth $17.2 million with a fifth-year team option. Minnesota taking Jackson with the 24th-overall pick came as a bit of a surprise on draft night, but the Vikings needed offensive line help and Jackson was considered worthy of a first-round pick by some draftniks. He was primarily a left guard at Ohio State but successfully kicked out to tackle for the bulk of his senior season. Jackson is likely fated for guard duties in Minnesota, but the positional versatility remains a plus.
Titans claimed Anfernee Orji off waivers from the Saints.
Orji played primarily on special teams in New Orleans but was credited with two starts across 16 appearances. He totaled 30 combined tackles and a pair of TFLs. Orji will need to continue seeing work on special teams to make the Titans’ roster.
Patriots signed RB Trayveon Williams, formerly of the Bengals.
Henderson was passed on the Cincinnati depth chart by Chase Brown last year and the team even traded for Khalil Herbert midseason. Despite having no role on offense, Williams was active for all 17 games as a special teamer. He will likely hold a similar role in New England if he cracks the team’s 53-man roster.
Free agent RB Jordan Mims worked out for the Patriots.
The Pats also worked out former Bengals running back Trayveon Williams. Mims ran 20 times for 70 yards in 2024 while adding 12 catches for 71 yards through the air. He also got some run on special teams. The Patriots are looking for some extra depth at running back, but there isn’t room for another fantasy-relevant option behind Rhamondre Stevenson and TreVeyon Henderson.
Jaguars signed TE Quintin Morris, formerly of the Bills, to a one-year contract.
Morris is purely a blocking tight end. He caught just 15 passes during his three years with the Bills, though he did manage to find the end zone three times. Morris will back up Brenton Strange in Jacksonville.