Elly De La Cruz PrizePicks MLB Picks Today, 4/22: Free DFS Picks & Projections

We have a full 15-game MLB slate Tuesday which gives us another fantastic opportunity to play on PrizePicks and start winning some money via MLB DFS Pick ‘Em contests.
The matchups today look really good, though you have to be looking at some of them from the right angle. If you’re looking for some late-night hammer picks then you should be targeting Athletics who get to play at home in Sutter Health Park tonight.
If you want to invest in pitching, then we’ve got some super-soft lineups and some heavy strikeout-prone lineups against some solid pitchers. Let’s see what looks good!
PrizePicks Fantasy Picks for Tuesday, April 22: MLB DFS Projections
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Elly De La Cruz MLB PrizePicks Fantasy Pick: More Than 1.5 Hits + Runs + RBI
There’s a little piece of me wondering if the 1.5 HRR is a trap here as De la Cruz continues to produce and Edward Cabrera is struggling to find his form after two very poor starts.
Elly has hit safely through six-straight and in eight of nine games recently with two home runs 10 RBI. He’s gone over the 1.5 HRR in seven of those nine games, so we’re going to ride this wave until it breaks. Cash it, baby!
Kris Bubic MLB PrizePicks Fantasy Pick: More Than 17.5 Outs
Despite only going 5.1 innings his last time out, we’re going back to the Bubic well and will happily use him on the total outs stat-line. The Royals lefty tossed three-straight quality starts to open the season and the only reason he was cut short his last outing; he was dealing with a Yankees lineup that hits lefties well.
This time around, he gets the Rockies who continue to be atrocious. Even better is that Colorado is striking out 31.4-percent of the ime, so as long as Bubic is throwing strikes, he should easily close out six full innings tonight.
- Pick: More Than 17.5 outs
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Player News
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.
José Soriano allowed three runs over five innings while not factoring in the decision Thursday against the Blue Jays.
Soriano left with a 4-3 lead, but it was erased quickly after his departure. The 26-year-old was not exactly dominant in his outing with eight hits allowed and four free passes, but he did strike out six to help balance things out a smidgen. Soriano takes an even ERA of 4.00 into a scheduled start against the Padres in San Diego on Tuesday. There should be better options for that one.