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Running Backs
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Derrick Henry, TEN- Not that this is a major surprise but with DeMarco Murray nursing an injury the lead back role should fall on the shoulders of Derrick Henry who has shown spurts of RB1 ability this season but has also struggled to fully take the job from Murray who has been injured for most of the year.
Matt Forte, NYJ- Back and forth we go between lead backs in New York with Forte having himself quite the day in Week 9. The Jets would be better served feeding Forte who has shown that there is still life in his legs this season when given consistent oppurtunity in the Jets offense.
Kenyan Drake, MIA- In Week 9 the Dolphins gave both Drake and Damien Williams a shot as the team's lead back and though Williams found then end zone as part of the team's passing attack it was Drake who ran better on the ground between the two. Drake also added six cathces for 35 yards to go along with his 69 yards rushing which should give him the edge heading into Week 10.
Wide Receivers
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DeSean Jackson/ Adam Humphries, TB- With Mike Evans suspended for Week 10 both Jackson and Humphries figure to see increased roles in the team's passing attack. These two receivers compliment each other as Jackson is known for stretching the field while Humphries is an underneath slot receiver. They draw favaorble matchup against the Jets in Week 10 and fantasy owners should check the waiver wire for Humphries as he has low ownerships on most platforms.
Josh Doctson, WAS- Doctson caught 3-of-5 targets for 59 yards in the Redskins win over the Seahawks in Week 9 with one of his catches being the main reason the team won in the first place as he showed off his downfield playmaking ability to dive for a deep 38 yard completion. With Terrelle Pryor seemingly out of the picture it looks as though Doctson is going to be given a chance to be a feature target in this offense.
Marquise Goodwin, SF- Many have already had Goodwin on their radar given his downfield playmaking ability but the season ending injury to Pierre Garcon prior to Week 9 should increase his role in the 49ers passing attack. In Week 9 without Garcon on the field Goodwin saw eight targets but only managed to grab two of them for 68 yards. The potential for Jimmy Garrapolo to take over as the team's starting quarterback should do wonders for Goodwin if that does ever actually occur this season.
Tight Ends
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Charles Clay, BUF- While Clay isn't esxaclty a "handcuff" he is coming back from injury and expected to play in Week 10. Clay was the favorite target of quarterback Tyrod Taylor and though he does have a new weapon in Kelvin Benjamin to throw the ball to I still feel like Clay and Taylor's prior connections should make Clay a nice tight end option to grab this week if he is floating around your league's waiver wire.