Michigan State vs. New Mexico Predictions, Picks & Odds: March Madness Second Round

The second round of March Madness presents an intriguing clash between the No. 2 seed Michigan State Spartans and the No. 10 seed New Mexico Lobos.
Both teams enter this matchup following strong performances in the first round, setting the stage for a showdown that will challenge Michigan State’s ability to contain New Mexico’s explosive offense. Let’s delve deeper into both teams as we prepare for Michigan St. vs. New Mexico picks.
Michigan St. vs. New Mexico Predictions For March Madness Second Round, 3/23
The Spartans secured a comfortable 87-62 victory over Bryant, showcasing their strength with a powerful second-half display. In contrast, New Mexico pulled off an upset against No. 7 seed Marquette, winning 75-66 by dominating the boards and applying intense defensive pressure.
This game highlights two distinct playing styles when looking at Michigan St. vs. New Mexico predictions: Michigan State focuses on rebounding and tight defense, while New Mexico thrives on fast-paced play and scoring during transitions.
Michigan State Spartans: Serious Title Contenders
Michigan State is well-equipped for a successful tournament run. The Spartans rank among the top defensive teams in the nation, limiting opponents to just 40.3% shooting overall and an impressive 27.9% from beyond the arc, which is the second-best in the country.
Under Tom Izzo's leadership, the team is hitting its stride, boasting a 9-1 record since mid-February. They recently defeated Bryant, pulling away in the second half. Coen Carr played a crucial role off the bench, contributing 18 points and nine rebounds.
While the Spartans don't heavily depend on three-point shooting (ranking 330th at 30.8%), they compensate with effective scoring inside and solid free-throw shooting at 78.1%, placing them 19th nationally.
New Mexico Lobos: Embracing The Underdog Role
New Mexico has fully embraced its role as an underdog, and their surprising victory over Marquette in the first round showcased their potential as a formidable opponent. The Lobos play at a high tempo and can score quickly, averaging 81.2 points per game, ranking 28th nationally.
The dynamic backcourt duo of Donovan Dent and Jamal Mashburn Jr. is particularly impressive. Dent, named Mountain West Player of the Year, expertly directs the offense, averaging 20.6 points and 6.4 assists per game. On the defensive end, New Mexico has made strides this season, limiting opponents to 70.8 points per game.
However, they have difficulty defending against three-point shots, allowing opponents to shoot 33.9% from that range, which could pose a challenge if Michigan State finds their rhythm from long distance.
How To Watch Second Round March Madness 2025
The exhilarating second round of the NCAA Tournament commenced yesterday, showcasing captivating matchups and memorable experiences.
To follow all the action, including our Michigan St. vs. New Mexico predictions for the game and other contests taking place today, there are numerous options available for viewing:
TV Channels
- CBS, TNT, TBS
Streaming Options
- March Madness Live, YouTube TV, Hulu + Live TV, Sling TV
Michigan vs. Texas A&M Game Details
- Date: Sunday, March 23, 2025
- Location: Ball Arena, Denver, CO
- Start Time: 8:40 PM ET
- TV: TNT
Michigan St. vs. New Mexico Odds, Spreads, Total & Betting Lines
DraftKings Sportsbook promptly released the Michigan St. vs. New Mexico odds and lines for the second-round matchup right after the announcement. Below are the most recent figures:
- Michigan State Spartans (+270) vs. New Mexico Lobos (-340)
- Spread: Michigan State -7.5 (-108) vs. New Mexico +7.5 (-110)
- Game Total: Over 148.5 (-110) vs. Under 148.5 (-110)
Michigan St. vs. New Mexico Spread Pick: Spartans -7.5 (-108 at DraftKings Sportsbook)
When looking to make Michigan St. vs. New Mexico picks, New Mexico boasts the standout player in Donovan Dent, but Michigan State is the stronger overall team. The Spartans have been impressive lately, winning nine out of their last ten games and covering the spread in seven of those.
Their defense is top-notch, ranking second in the nation for opponent three-point shooting at 27.9% and limiting teams to just 40.3% shooting overall. While New Mexico excels with a fast-paced offense, Michigan State can control the tempo and disrupt the Lobos' rhythm.
The Spartans are tough on the boards, ranking 11th in rebounding, and their organized defensive rotations will likely wear down New Mexico as the game goes on. Expect a close first half, with Dent keeping New Mexico competitive.
However, as the game continues, Michigan State's depth and defensive intensity will likely lead to a significant second-half advantage. The Spartans appear poised for a deep tournament run and should secure a win by double digits. We’ll bet on MSU -7.5 (-108 at DraftKings Sportsbook) for our Michigan St. vs. New Mexico predictions.
Michigan St. vs. New Mexico Injury Report & Starting Lineup
Michigan State Spartans Injury Report
- C. Walton - F - Out - Redshirt
Michigan State Spartans Projected Starters
- J. Akins - 12.7 PPG, 3.6 RPG
- J. Richardson - 12.0 PPG, 3.2 RPG
- J. Fears - 7.4 PPG, 5.5 APG
- J. Kohler - 8.0 PPG, 7.6 RPG
- T. Holloman - 9.0 PPG, 3.8 APG
New Mexico Lobos Injury Report
- S. Douma-Sanchez - G - Out - Shoulder
New Mexico Lobos Projected Starters
- D. Dent - 20.6 PPG, 6.4 APG
- N. Joseph - 14.0 PPG, 11.2 RPG
- M. Amzil - 11.3 PPG, 5.4 RPG
- T. Washington - 11.2 PPG, 3.9 RPG
- C. Noland - 8.0 PPG, 2.5 RPG
How To Bet On Michigan St. vs. New Mexico At DraftKings & Claim $200 In Bonus Bets
You will not be required to enter a specific DraftKings promo code for March Madness when you register through our platform, allowing you to begin immediately. By taking advantage of today’s DraftKings promotion, you will qualify for $200 in bonus bets, regardless of whether you choose to wager on our Michigan St. vs. New Mexico predictions.
However, selecting a significant upset could be beneficial, as you will still receive your bonus even if your qualifying bet does not win. Your initial bet, which must be at least $5, will serve as your qualifying wager.
Since it is not necessary for this bet to win in order for you to receive the $200 in bonus bets, you can enjoy the excitement of March Madness while hoping for two substantial payouts. Regardless of the outcome, ensure you secure a 40x boost by activating today’s DraftKings promo code for March Madness through this link.
Player News
Dolphins signed No. 13 overall pick DT Kenneth Grant to a four-year contract.
ESPN’s Jeremy Fowler reports that Grant will sign his contract today. The former Michigan defensive tackle is expected to fill a major void left by Christian Wilkins, who left for the Raiders in the 2024 offseason. Grant totaled 32 tackles, three sacks, and seven TFLs in his final season at Michigan and excelled at stopping the run while also generating 27 pressures in his final season, per PFF.
Daulton Varsho picked up three hits, three RBI and a homer in a win over the Angels on Thursday.
Varsho has only played in seven games this year, but they’ve been seven good ones. He’s homered three times already, and his slugging percentage is a remarkable — and entirely unsustainable — .727 over 22 at-bats. Varsho has been a mediocre offensive player in his two seasons with the Blue Jays, but it’s possible at the age of 28 he’s having a breakout campaign. Far from a guarantee, but possible.
Taylor Ward hit a two-run homer in a loss to the Blue Jays on Thursday.
Ward, 31, gave the Angels a 2-0 lead with a two-run homer off Chris Bassitt in the first inning. He’s now gone deep in two of his last three games, and it ‘improves’ his slash to .181/.224/.391. Ward has been one of the most hot/cold players players in the sport over the last few years, so fantasy managers who can afford to make some roster moves may want to look at Ward while the going is good.
Vladimir Guerrero Jr. picked up three hits and scored twice in an 8-5 win over the Angels on Thursday.
Guerrero also drew a walk. It gives the first baseman multiple hits in back-to-back games, and it’s the third time in May that he’s reached that mark. That’s helped raise his average from .268 to .295, and the only thing fantasy managers can be disappointed with is his .432 slugging percentage. That number should continue to climb as the season unfolds, but Vladdy Jr. has had some inconsistent seasons when it comes to power production.
Chad Green picked up his first save of 2025 with a scoreless ninth against the Angels on Thursday.
Green got the save after Jeff Hoffman worked in back-to-back games — and struggled — in the first two contests against the Angels. He struck out two and looked the part while needing just nine pitches to get through the inning. Hoffman should remain the closer, but Green is on his tail if the struggles were to continue.
Chris Bassitt allowed five runs — four earned — while working six-plus innings against the Angels on Thursday while picking up a win.
Bassitt allowed three runs over the first two innings on a pair of homers, but settled down over his next four frames. He came out to work the seventh, but ended up being charged for two more runs after leaving the contest. The 36-year-old veteran has forged a 3.35 ERA and outstanding 49/8 K/BB ratio over the first quarter of the season, but this wasn’t him at his best. He’ll get the Rays next week if the rotation order stays the same for Toronto.