March Madness Sweet 16 Day 2: Expert Picks, Schedule, How To Watch & Odds

The intensity of March Madness is escalating as we enter the Sweet 16 stage, where the competition becomes increasingly fierce and the stakes are heightened. Following an exhilarating night of games yesterday, the NCAA Tournament proceeds today with eight teams competing for the opportunity to advance to the Elite Eight.
With formidable programs, rising talents, and unexpected narratives from teams such as Michigan and Ole Miss still in contention, the excitement is at its zenith. For college basketball enthusiasts and those interested in wagering, the Sweet 16 presents essential matchups, significant betting opportunities, and expert analyses for each game.
This article will provide the complete schedule, March Madness Sweet 16 picks, viewing options, and the latest betting odds, ensuring you are well-prepared for the forthcoming action.
March Madness Sweet 16 Schedule For Today, 3/28
Before getting into March Madness Sweet 16 picks, here is the lineup for today's games in the NCAA Tournament:
- (2) Michigan State vs. (6) Ole Miss, 7:09 p.m. | CBS
- (2) Tennessee vs. (3) Kentucky, 7:39 p.m. | TBS
- (1) Auburn vs. (5) Michigan, 9:39 p.m. | CBS
- (1) Houston vs. (4) Purdue, 10:09 p.m. | TBS
March Madness Sweet 16 Expert Picks & Best Bets
Michigan State vs. Ole Miss Prediction Today, 3/28: March Madness Sweet 16
Michigan State approaches the Sweet 16 as a 3.5-point favorite, bolstered by a defensive prowess that has characterized Tom Izzo’s success in March. The Spartans are ranked among the top 10 nationally for adjusted defensive efficiency, creating challenges for opposing scorers.
On the offensive end, Tre Holloman and Jace Richardson have been reliable leaders in the backcourt, while Coen Carr’s versatility offers a dual threat for scoring both inside and outside. If they can dominate the boards and minimize turnovers, Michigan State possesses the necessary tools to secure another victory in the tournament.
Conversely, Ole Miss, the underdog in this contest, has advanced by utilizing a fast-paced offense and effective perimeter shooting. The Rebels, spearheaded by Sean Pedulla and Jaemyn Brakefield, have consistently exploited defenses with high-percentage shots from beyond the arc. Their ability to stretch the floor will be crucial against Michigan State’s robust defense.
Defensively, Ole Miss must effectively manage the Spartans’ pick-and-roll plays and limit second-chance points. While Michigan State’s defensive strength and tournament experience position them as the favorites, an upset could occur if Ole Miss finds their rhythm from three-point range.
- Expert March Madness Sweet 16 Picks: Spartans -3.5 (-110 at BetMGM)
Tennessee vs. Kentucky Prediction Today, 3/28: March Madness Sweet 16
Kentucky enters the matchup as a 3.5-point underdog against Tennessee in a clash of SEC titans. The Wildcats excel in offensive efficiency, driven by Koby Brea and Otega Oweh, who lead a potent scoring offense. They are known for their fast-paced play, ranking among the elite in transition offense; however, their defensive inconsistency has been a significant weakness.
To secure an upset, Kentucky must improve their interior defense and minimize Tennessee's second-chance points. On the other hand, Tennessee, the favored team, employs a tough, methodical approach, guided by experienced point guard Zakai Zeigler.
Their defense is among the top five in adjusted efficiency, and their rebounding prowess could create challenges for Kentucky. The Volunteers methodically execute half-court plays, leveraging their size to exhaust opponents throughout the game.
Ultimately, this matchup hinges on tempo—if Kentucky can accelerate the game and push Tennessee into a high-scoring affair, they stand a chance to cover the spread and possibly win. Conversely, if Tennessee controls the pace with its half-court defense, they are likely to prevail.
- Expert March Madness Sweet 16 Picks: Wildcats +3.5 (-110 at BetMGM)
How To Watch 2025 March Madness Sweet 16 Games
There are plenty of ways for fans to catch the live action and follow along with any March Madness Sweet 16 picks that are made:
- CBS and TBS: Tune into your local CBS or TBS stations to watch the games, or stream them through services like Paramount+, YouTube TV, Hulu + Live TV, and Sling TV.
- March Madness Live: This is the official streaming platform of the NCAA, providing coverage for all the games.
2025 March Madness Sweet 16 Odds & Betting Lines Via BetMGM Sportsbook
Check out the current betting odds for today’s games, brought to you by BetMGM Sportsbook:
- Michigan State Spartans (-2.5) vs. Ole Miss Rebels – O/U 150.5
- Tennessee Volunteers (-3.5) vs. Kentucky Wildcats – O/U 144
- Auburn Tigers (-7.5) vs. Michigan Wolverines – O/U 170
- Houston Cougars (-5.5) vs. Purdue Boilermakers – O/U 149
As the March Madness Sweet 16 unfolds, get ready for fierce competitions, exhilarating conclusions, and surprising turns. Keep the excitement alive with some March Madness Sweet 16 picks as we gear up for the Final Four!
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