Florida vs. Houston Predictions, Picks & Odds: NCAA Tournament Championship

The thrilling journey of March Madness reaches its peak in San Antonio, where the Florida Gators will face off against the Houston Cougars for the 2025 NCAA Tournament National Championship.
This matchup features two top-seeded teams ready to deliver an intense battle. With their legacies at stake and a championship title on the line, let’s explore the crucial matchups, betting odds, and expert Florida vs. Houston predictions for the highly anticipated showdown between the Gators and the Cougars.
Florida vs. Houston Predictions For NCAA Tournament Championship, 4/7
Both squads have earned their spots in the title game through tough victories in the Final Four – Florida, led by the impressive Walter Clayton Jr., who scored 34 points to defeat Auburn, and Houston, which pulled off an incredible comeback against Duke, finishing with a 15-3 run in the closing minutes to quiet the Blue Devils and their expected No. 1 NBA Draft pick.
All that said, how do their previous games in the tournament matter for us when making Florida vs. Houston picks for tonight?
Florida Gators: The Best Team In The Best Conference
Florida has been scoring 85 points a game like its second nature, dominating the SEC with a combination of confidence, size, and impressive shooting. They don’t just win games – they make a statement, racking up 90-point performances like they’re collecting trophies.
Walter Clayton has been on fire this March/April, and the Gators have a deep lineup that keeps the pressure on their opponents. But it’s not only about scoring; their top-notch defense shuts down three-point shots and punishes mistakes.
In the toughest league in the country, they’ve emerged as the champions. Now, they’re heading into the final game of the season with the experience, momentum, and talent to seal the deal.
Houston Cougars: Giving A “Team Of Destiny” Vibe
Every tournament has that one team – the one that makes it through tough challenges, wins intense battles, and starts to seem unstoppable. That’s Houston. They don’t just play basketball; they fight for every point.
The Cougars have the best defense in the nation, but what really sets them apart is how they shine in critical moments – beating Duke and quieting Purdue makes it seem like they’re destined for greatness. L.J. Cryer has been hitting three-pointers like a pro, and Milos Uzan is shooting with incredible accuracy.
They’ve taken down powerful teams without, at times, even breaking a sweat as well. It might not always be pretty, but Houston is ready for this. Every bounce and every lucky break – right now, it all seems to be going their way.
How To Watch NCAA Tournament Championship 2025
The 2025 National Championship game is happening today, featuring the highest of stakes and unforgettable moments.
To keep up with all the action, including our Florida vs. Houston predictions for the matchup, there are various ways to follow the events:
TV Channels
- CBS
Streaming Options
- YouTube TV, Hulu + Live TV, Sling TV
Florida vs. Houston Game Details
- Date: Monday, April 7, 2025
- Location: Alamodome, San Antonio, TX
- Start Time: 8:50 PM ET
- TV: CBS
Florida vs. Houston Odds, Spreads, Total & Betting Lines
Novig quickly published the Florida vs. Houston odds and lines for the National Championship game as soon as the matchup was finalized.
Here are the latest numbers:
- Florida Gators (-104) vs. Houston Cougars (+102)
- Spread: Florida -1.5 (+109) vs. Houston +1.5 (-116)
- Game Total: Over 141.5 (+106) vs. Under 141.5 (-115)
Florida vs. Houston Winner Prediction: Cougars ML (+102 at Novig)
Let me break this down for you: I’m all in on Houston’s money line (+102 at Novig) with my Florida vs. Houston picks, and I’m not second-guessing it. With this line, that feels like a steal. I’m backing the top defense in the nation, allowing just 58.4 points per game, and I’m getting it at plus odds?
Going up against a Florida team that thrives on chaotic play and high-scoring games? No way. Not with this Kelvin Sampson squad. Houston isn’t here to play fast – they’re here to take you down with their defense, discipline, and precise shooting.
Florida has been good, no doubt. But just look at the teams Houston has already taken down – Duke, Tennessee, Purdue. That’s a lineup of March heavyweights, and Houston keeps showing up like tax season.
While Florida is scoring 85 points a game, Houston is keeping opponents 20+ points below their average. That’s not just luck; that’s a solid strategy. In short: Florida can try to run, but they won’t escape. I’m backing the Cougs ML (+102 at Novig) in my Florida vs. Houston predictions.
Florida vs. Houston Injury Report & Starting Lineup
Florida Gators Injury Report
- None
Florida Gators Projected Starters
- W. Clayton Jr. (G): 24.6 PPG, 50.0 FG%
- A. Martin (G): 15.2 PPG, 4.6 RPG
- T. Haugh (F): 13.0 PPG, 7.4 RPG
- W. Richard (G): 10.2 PPG, 4.4 RPG
- A. Condon (F-C): 6.2 PPG, 5.4 RPG
Houston Cougars Injury Report
- None
Houston Cougars Projected Starters
- L. Cryer (G): 18.6 PPG, 45.2 3P%
- E. Sharp (G): 13.8 PPG, 1.6 SPG
- M. Uzan (G): 11.6 PPG, 4.4 APG
- J. Roberts (F): 9.8 PPG, 7.4 RPG
- J. Tugler (F): 4.6 PPG, 7.2 RPG
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